Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 11/20 | 0.56 |
| ▸ | AKR1C2 | P52895 | 11/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.53 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.53 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.53 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.53 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.53 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.53 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP7 | P09237 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29010056 | 0.82 | AKR1C3 (0.47) | AKR1C3AKR1C2PTGS2 | |
| SCHEMBL6270587 | 0.80 | AKR1C3 (0.63) | AKR1C3AKR1C2PTGS2PSEN1PSEN2 | |
| SCHEMBL11960749 | 0.78 | AKR1C3 (0.60) | AKR1C3AKR1C2PTGS2PSEN1PSEN2 | |
| SCHEMBL1797371 | 0.77 | AKR1C3 (0.65) | AKR1C3AKR1C2PTGS2PSEN1PSEN2 | |
| SCHEMBL31301420 | 0.75 | MKNK1 (0.62) | KDM1AHDAC1MAP4K4 | |
| SCHEMBL1843427 | 0.75 | MKNK1 (0.62) | KDM1AHDAC1MAP4K4 | |
| SCHEMBL2161512 | 0.74 | AKR1C3 (0.59) | AKR1C3AKR1C2PTGS2PSEN1PSEN2 | |
| SCHEMBL13876033 | 0.72 | KDM1A (0.54) | KDM1AHDAC1MAP4K4 | |
| SCHEMBL1372793 | 0.72 | AKR1C3 (1.00) | AKR1C3AKR1C2PTGS2PSEN1PSEN2 | |
| SCHEMBL9895027 | 0.71 | RXRA (0.57) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2435428-B1 | SUBSTITUTED PIPERIDINES | BAYER IP GMBH (DE) | 2013-07-31 | — | — | EP | disclosed |
| WO-2010136128-A1 | SUBSTITUTED PIPERIDINES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-12-02 | — | — | WO | disclosed |