Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.51 |
| ▸ | HTR2C | P28335 | 4/20 | 0.51 |
| ▸ | HTR2B | P41595 | 4/20 | 0.51 |
| ▸ | PBRM1 | Q86U86 | 9/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11358726 | 0.82 | HTR2A (0.54) | HTR2AHTR2CHTR2BPBRM1GAA | |
| SCHEMBL12716352 | 0.77 | HTR2A (0.55) | HTR2AHTR2CHTR2BPBRM1GAA | |
| SCHEMBL30451265 | 0.74 | HTR2C (0.56) | HTR2AHTR2CHTR2BPBRM1GAA | |
| SCHEMBL12718314 | 0.72 | HTR2A (0.51) | HTR2AHTR2CHTR2BPBRM1GAA | |
| SCHEMBL11354534 | 0.71 | CYP1A2 (0.48) | HTR2AHTR2CHTR2BPBRM1GAA | |
| SCHEMBL11358191 | 0.70 | HTR2A (0.46) | HTR2AHTR2CHTR2BPBRM1GAA | |
| SCHEMBL3748724 | 0.69 | HTR2A (0.48) | HTR2AHTR2CHTR2BPBRM1GAA | |
| SCHEMBL13756918 | 0.68 | HTR2A (1.00) | HTR2AHTR2CHTR2B | |
| SCHEMBL13756919 | 0.68 | HTR2A (1.00) | HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL4467236 | 0.67 | HTR2A (1.00) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423710-B | Novel heterocyclic tricyclic derivative compounds and use thereof | 韩美药品株式会社 | 2024-06-14 | — | — | CN | disclosed |
| CN-116194108-A | Novel dioxoisoquinolinone derivatives and use thereof | 韩美药品株式会社 | 2023-05-30 | — | — | CN | disclosed |