Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.56 |
| ▸ | HTR2A | P28223 | 4/20 | 0.56 |
| ▸ | HTR2B | P41595 | 4/20 | 0.56 |
| ▸ | PBRM1 | Q86U86 | 5/20 | 0.50 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30451575 | 0.85 | AURKA (0.44) | HTR2CHTR2AHTR2BPBRM1TNKS2 | |
| SCHEMBL29016841 | 0.80 | PBRM1 (0.60) | HTR2CHTR2AHTR2BPBRM1TNKS2 | |
| SCHEMBL12716352 | 0.78 | HTR2A (0.55) | HTR2CHTR2AHTR2BPBRM1TNKS2 | |
| SCHEMBL11358726 | 0.76 | HTR2A (0.54) | HTR2CHTR2AHTR2BPBRM1TNKS2 | |
| SCHEMBL29010215 | 0.74 | HTR2A (0.51) | HTR2CHTR2AHTR2BPBRM1TNKS2 | |
| SCHEMBL12718314 | 0.74 | HTR2A (0.51) | HTR2CHTR2AHTR2BPBRM1TNKS2 | |
| SCHEMBL13756918 | 0.72 | HTR2A (1.00) | HTR2CHTR2AHTR2B | |
| SCHEMBL13756919 | 0.72 | HTR2A (1.00) | HTR2CHTR2AHTR2B | |
| SCHEMBL30451582 | 0.71 | TNKS2 (0.47) | HTR2CHTR2AHTR2BPBRM1TNKS2 | |
| Hydrochloric Acid SCHEMBL4467236 | 0.71 | HTR2A (1.00) | HTR2CHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116261562-A | PI 3K-alpha inhibitors and methods of use thereof | 传达治疗有限公司 | 2023-06-13 | — | — | CN | disclosed |