Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29010796 | 0.98 | HCAR1 (0.36) | MGLLGSK3AGSK3BHCAR1GMNN | |
| SCHEMBL718672 | 0.98 | HCAR1 (0.36) | MGLLGSK3AGSK3BHCAR1GMNN | |
| SCHEMBL29010970 | 0.98 | HCAR1 (0.36) | MGLLGSK3AGSK3BHCAR1GMNN | |
| SCHEMBL29010976 | 0.95 | MGLL (0.36) | MGLLGSK3AGSK3BHCAR1GMNN | |
| SCHEMBL29010932 | 0.90 | MGLL (0.39) | MGLLGSK3AGSK3BGMNNALDH1A1 | |
| Cyclohexane SCHEMBL28396853 | 0.78 | ALDH1A1 (0.33) | MGLLGSK3AGSK3BALDH1A1LMNA | |
| SCHEMBL7943976 | 0.78 | ALDH1A1 (0.33) | MGLLGSK3AGSK3BALDH1A1LMNA | |
| SCHEMBL29246382 | 0.76 | CHRM2 (0.33) | — | |
| SCHEMBL23346552 | 0.74 | MGLL (0.35) | MGLLGSK3AGSK3BGMNNALDH1A1 | |
| SCHEMBL1028008 | 0.74 | OPRL1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116199747-A | Lidamycin prodrug, preparation method and application thereof in preparation of antitumor drugs | 中国医学科学院医药生物技术研究所 | 2023-06-02 | — | — | CN | disclosed |