SCHEMBL29010807

SCHEMBL29010807

O=Cc1cc(N(c2ccccc2)c2ccccc2)c(C=O)c(C=O)c1C=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.37
TDP1 Q9NUW8 2/20 0.37
MEN1 O00255 2/20 0.37
LMNA P02545 2/20 0.37
THRB P10828 1/20 0.37
BLM P54132 1/20 0.37
APP P05067 1/20 0.33
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
ALDH1A1 P00352 6/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
KDM4E B2RXH2 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
MAPT P10636 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
TSHR P16473 1/20 0.31
TRIM24 O15164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30456706 1.00 KMT2A (0.37) KMT2ATDP1MEN1LMNATHRB
SCHEMBL4141360 0.84 KMT2A (0.38) KMT2ATDP1MEN1LMNATHRB
SCHEMBL279011 0.83 KMT2A (0.44) KMT2ATDP1MEN1LMNATHRB
SCHEMBL29613044 0.76 KMT2A (0.43) KMT2ATDP1MEN1LMNATHRB
SCHEMBL7605635 0.76 KMT2A (0.43) KMT2ATDP1MEN1LMNATHRB
SCHEMBL50149 0.75 KMT2A (0.50) KMT2ATDP1MEN1LMNATHRB
SCHEMBL28734034 0.71 ERN1 (0.34) KMT2ATDP1MEN1APPALDH1A1
SCHEMBL28806146 0.71 ALDH1A1 (0.40) KMT2ATDP1MEN1LMNATHRB
SCHEMBL31298129 0.71 KMT2A (0.50) KMT2ATDP1MEN1LMNATHRB
SCHEMBL9249886 0.70 MEN1 (0.39) KMT2ATDP1MEN1LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116174047-A Covalent organic compound loaded monoatomic cobalt catalyst and preparation method and application thereof 广东工业大学 2023-05-30 CN claimed
CN-116174047-B Covalent organic compound loaded monoatomic cobalt catalyst and preparation method and application thereof 广东工业大学 2024-05-24 CN disclosed
CN-116174047-A Covalent organic compound loaded monoatomic cobalt catalyst and preparation method and application thereof 广东工业大学 2023-05-30 CN disclosed