SCHEMBL50149

SCHEMBL50149

O=Cc1ccccc1N(c1ccccc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.50
LMNA P02545 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
MEN1 O00255 2/20 0.50
THRB P10828 1/20 0.50
BLM P54132 1/20 0.50
ALDH1A1 P00352 7/20 0.41
TSHR P16473 1/20 0.41
TRIM24 O15164 1/20 0.41
TRIM33 Q9UPN9 1/20 0.41
GAA P10253 1/20 0.39
APP P05067 1/20 0.38
HPGD P15428 1/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CYP2A6 P11509 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
KDM4E B2RXH2 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31298129 0.96 KMT2A (0.50) KMT2ALMNATDP1MEN1THRB
SCHEMBL30825194 0.89 KMT2A (0.40) KMT2ALMNATDP1MEN1THRB
SCHEMBL374886 0.86 LMNA (0.60) KMT2ALMNATDP1MEN1THRB
SCHEMBL6311737 0.85 ALDH1A1 (0.51) KMT2ALMNAMEN1ALDH1A1TSHR
SCHEMBL3652788 0.84 ALDH1A1 (0.45) KMT2ALMNATDP1MEN1THRB
SCHEMBL29613044 0.84 KMT2A (0.43) KMT2ALMNATDP1MEN1THRB
SCHEMBL30825175 0.84 LMNA (0.43) KMT2ALMNATDP1MEN1THRB
SCHEMBL30022854 0.84 ALDH1A1 (0.45) KMT2ALMNATDP1MEN1THRB
SCHEMBL7605635 0.84 KMT2A (0.43) KMT2ALMNATDP1MEN1THRB
SCHEMBL4728239 0.84 KMT2A (0.39) KMT2ALMNATDP1MEN1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220257483-A1 INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL HENKEL AG & CO. KGAA (DE) 2022-08-18 US claimed
CN-110407718-B Benzoylimide derivative with triphenylamine as donor, and preparation and application thereof 浙江工业大学 2022-07-26 CN claimed
CN-113912579-B Rhodamine compound, preparation method thereof and application thereof in detection of microcystins 云南大学 2022-04-12 CN claimed
CN-113912579-A Rhodamine compound, preparation method thereof and application thereof in detection of microcystins 云南大学 2022-01-11 CN claimed
US-20100094056-A1 ARYLAMINE-SUBSTITUTED DIVINYL FLUORENES AND THEIR USE FOR ELECTROPHOTOGRAPHIC APPLICATIONS, AND FOR OLEDS (ORGANIC LIGHT EMITTING DEVICES) SENSIENT IMAGING TECHNOLOGIES GMBH (DE) 2010-04-15 US claimed
EP-2118049-A1 ARYLAMINE-SUBSTITUTED DIVINYL FLUORENES AND THEIR USE FOR ELECTROPHOTOGRAPHIC APPLICATIONS, AND FOR OLEDS (ORGANIC LIGHT EMITTING DEVICES) Sensient Imaging Technologies GmbH (DE) 2009-11-18 EP claimed
WO-2008071376-A1 ARYLAMINE-SUBSTITUTED DIVINYL FLUORENES AND THEIR USE FOR ELECTROPHOTOGRAPHIC APPLICATIONS, AND FOR OLEDS (ORGANIC LIGHT EMITTING DEVICES) SENSIENT IMAGING TECHNOLOGIES GMBH (DE) 2008-06-19 WO claimed
EP-1432428-A1 Agent for colouring fibres containing keratin Henkel Kommanditgesellschaft auf Aktien (DE) 2004-06-30 EP claimed
WO-2003030842-A1 AGENT FOR COLOURING FIBRES CONTAINING KERATIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-04-17 WO claimed
JP-4253962-A None JP disclosed
WO-2026102095-A1 METHODS FOR DETECTING PER- OR POLY-FLUOROALKYL SUBSTANCES WITH FLUOROPHORES UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2026-05-15 WO disclosed
US-20250210639-A1 COMPOSITION FOR FORMING AN ACTIVE MATERIAL COMPOSITE, AN ACTIVE MATERIAL COMPOSITE, AND A METHOD FOR PRODUCING AN ACTIVE MATERIAL COMPOSITE NISSAN CHEMICAL CORPORATION (JP) 2025-06-26 US disclosed
US-12148915-B2 Composition for forming an active material composite, an active material composite, and a method for producing an active material composite NISSAN CHEMICAL CORPORATION (JP) 2024-11-19 US disclosed
US-20240379967-A1 COMPOSITION FOR FORMING THIN FILM FOR ENERGY STORAGE DEVICE ELECTRODE NISSAN CHEMICAL CORPORATION (JP) 2024-11-14 US disclosed
EP-0337307-A2 Electrophotographic photoreceptor KONICA CORPORATION (JP) 1989-10-18 EP disclosed
EP-0063528-B1 CONDENSATION POLYMERIC PHOTOCONDUCTORS CONTAINING PENDANT ARYLAMINES, PHOTOCONDUCTIVE COMPOSITIONS AND ELECTROPHOTOGRAPHIC ELEMENTS CONTAINING THESE PHOTOCONDUCTORS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1987-08-19 EP disclosed
US-4463078-A POLYESTER COATINGS AND FILMS; ELECTROGRAPHY; XEROGRAPHY; LIGHT SEN EASTMAN KODAK COMPANY (US) 1984-07-31 US disclosed
US-4424266-A Layered electrophotographic photosensitive element having hydrazone charge transport material KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-01-03 US disclosed
US-4395475-A Condensation polymeric photoconductors containing pendant arylamines EASTMAN KODAK COMPANY (US) 1983-07-26 US disclosed
EP-0063528-A2 Condensation polymeric photoconductors containing pendant arylamines, photoconductive compositions and electrophotographic elements containing these photoconductors EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1982-10-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100094056-A1 ARYLAMINE-SUBSTITUTED DIVINYL FLUORENES AND THEIR USE FOR ELECTROPHOTOGRAPHIC APPLICATIONS, AND FOR OLEDS (ORGANIC LIGHT EMITTING DEVICES) OCIAD2, OCIAD1, TRPA1 KMT2A 1958/4885LMNA 1641/4885TDP1 710/4885
US-20220257483-A1 INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL KRT18, VIM, CDH1 KMT2A 172/4885LMNA 47/4885TDP1 3850/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.