SCHEMBL7605635

SCHEMBL7605635

O=Cc1cccc(N(c2ccccc2)c2ccccc2)c1C=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.43
TDP1 Q9NUW8 3/20 0.43
MEN1 O00255 3/20 0.43
LMNA P02545 2/20 0.43
THRB P10828 1/20 0.43
BLM P54132 1/20 0.43
APP P05067 1/20 0.37
ALDH1A1 P00352 7/20 0.36
TSHR P16473 1/20 0.36
TRIM24 O15164 1/20 0.36
TRIM33 Q9UPN9 1/20 0.36
GAA P10253 1/20 0.35
ERN1 O75460 2/20 0.34
HPGD P15428 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.32
KDM4E B2RXH2 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29613044 1.00 KMT2A (0.43) KMT2ATDP1MEN1LMNATHRB
SCHEMBL4141360 0.85 KMT2A (0.38) KMT2ATDP1MEN1LMNATHRB
SCHEMBL50149 0.84 KMT2A (0.50) KMT2ATDP1MEN1LMNATHRB
SCHEMBL31298129 0.80 KMT2A (0.50) KMT2ATDP1MEN1LMNATHRB
SCHEMBL4307749 0.80 ERN1 (0.50) KMT2ATDP1MEN1LMNATHRB
SCHEMBL30456706 0.76 KMT2A (0.37) KMT2ATDP1MEN1LMNATHRB
SCHEMBL29010807 0.76 KMT2A (0.37) KMT2ATDP1MEN1LMNATHRB
SCHEMBL279011 0.76 KMT2A (0.44) KMT2ATDP1MEN1LMNATHRB
SCHEMBL3287210 0.76 APP (0.47) KMT2ATDP1MEN1LMNATHRB
SCHEMBL19774528 0.76 ALDH1A1 (0.38) TDP1ALDH1A1TSHRL3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114573818-A Preparation method of hydrogen-containing POSS (polyhedral oligomeric silsesquioxane) functionalized modified triphenylamine-based hybrid porous material 刘海龙 2022-06-03 CN claimed
CN-103554448-A Polymeric metal complex containing triphenylamine, synthetic method of polymeric metal complex and application of polymeric metal complex in dye-sensitized solar cells UNIV XIANGTAN 2014-02-05 CN claimed
CN-114605636-A Preparation method of MOSS (metal oxide-silicon) functionalized modified triphenylamine-based hybrid porous material 曾秀秋 2022-06-10 CN disclosed
CN-114573818-A Preparation method of hydrogen-containing POSS (polyhedral oligomeric silsesquioxane) functionalized modified triphenylamine-based hybrid porous material 刘海龙 2022-06-03 CN disclosed
CN-114573818-A Preparation method of hydrogen-containing POSS (polyhedral oligomeric silsesquioxane) functionalized modified triphenylamine-based hybrid porous material 刘海龙 2022-06-03 CN disclosed
CN-114524936-A Preparation method of chloromethyl POSS (polyhedral oligomeric silsesquioxane) functionalized modified triphenylamine-based hybrid porous material 荣往 2022-05-24 CN disclosed
CN-105399720-B 9,9 ' (N phenyl N, N 4,4 ' diphenyl) double fluorone reagents and its preparation method and application 山西大同大学 2017-06-13 CN disclosed
CN-103554448-A Polymeric metal complex containing triphenylamine, synthetic method of polymeric metal complex and application of polymeric metal complex in dye-sensitized solar cells UNIV XIANGTAN 2014-02-05 CN disclosed
EP-0938514-B1 ORDERED POLY(ARYLENE VINYLENE) TERPOLYMERS, METHOD FOR THE PRODUCTION AND THE USE THEREOF AS ELECTROLUMINESCENT MATERIALS COVION ORGANIC SEMICONDUCTORS (DE) 2002-12-18 EP disclosed
US-6316591-B1 FOR USE IN LIGHTING OR DISPLAY DEVICES; SOLID-STATE LIGHT SOURCES AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) 2001-11-13 US disclosed
EP-0812820-B1 TRIPHENYLAMINE DERIVATIVES, AND CHARGE TRANSPORT MATERIAL AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM TAKASAGO PERFUMERY CO LTD (JP) 2001-01-17 EP disclosed
US-6172264-B1 REACTING A TRIPHENYLAMINE WITH A VILSMEIER IN PRESENCE OF ACID CATALYST TAKASAGO INTERNATIONAL CORPORATION (JP) 2001-01-09 US disclosed
US-5989765-A CHARGE TRANSPORT MATERIAL IS A TRIPHENYLAMINE DERIVATIVE WHERE ONE OF THE PHENYL GROUPS OF THE TRIPHENYL AMINE HAS A DIPHENYLBUTADIENYL-SUBSTITUENT AND THE OTHER TWO PHENYL GROUPS HAVE A DIPHENYLBUTADIENYL- OR DIPHENYLVINYL-FRAMEWORK TAKASAGO INTERNATIONAL CORPORATION (JP) 1999-11-23 US disclosed
EP-0938514-A1 ORDERED POLY(ARYLENE VINYLENE) TERPOLYMERS, METHOD FOR THE PRODUCTION AND THE USE THEREOF AS ELECTROLUMINESCENT MATERIALS Aventis Research & Technologies GmbH & Co. KG (DE) 1999-09-01 EP disclosed
US-5910610-A Triphenylamine derivative, charge-transporting material comprising the same, and electrophotographic photoreceptor TAKASAGO INTERNATIONAL CORPORATION (JP) 1999-06-08 US disclosed
WO-1998021262-A1 ORDERED POLY(ARYLENE VINYLENE) TERPOLYMERS, METHOD FOR THE PRODUCTION AND THE USE THEREOF AS ELECTROLUMINESCENT MATERIALS AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) 1998-05-22 WO disclosed
EP-0812820-A1 TRIPHENYLAMINE DERIVATIVES, AND CHARGE TRANSPORT MATERIAL AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM Takasago International Corporation (JP) 1997-12-17 EP disclosed