Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 7/20 | 0.83 |
| ▸ | EGFR | P00533 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29010903 | 0.91 | TNKS2 (1.00) | TNKS2EGFRMAPTGAAKDM4E | |
| SCHEMBL29010775 | 0.89 | TNKS2 (0.83) | TNKS2EGFRMAPTGAAKDM4E | |
| SCHEMBL29010778 | 0.89 | TNKS2 (0.83) | TNKS2EGFRMAPTGAAKDM4E | |
| SCHEMBL29010896 | 0.89 | TNKS2 (0.83) | TNKS2EGFRMAPTGAAKDM4E | |
| SCHEMBL29010909 | 0.88 | TNKS2 (0.78) | TNKS2EGFRMAPTGAAKDM4E | |
| SCHEMBL29010779 | 0.87 | TNKS2 (0.81) | TNKS2EGFRMAPTKDM4EALDH1A1 | |
| SCHEMBL30230638 | 0.81 | ALDH1A1 (0.71) | TNKS2EGFRMAPTGAAKDM4E | |
| SCHEMBL28992907 | 0.81 | ALDH1A1 (0.71) | TNKS2EGFRMAPTGAAKDM4E | |
| SCHEMBL2821455 | 0.79 | TNKS2 (0.72) | TNKS2MAPTGAAKDM4EALDH1A1 | |
| SCHEMBL27925475 | 0.79 | TNKS2 (0.72) | TNKS2MAPTGAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178283-B | 2-Phenyl-2, 3-dihydro-quinazolin-4 (1H) -one derivative, preparation and application thereof | 武汉科技大学 | 2024-07-02 | — | — | CN | disclosed |
| CN-116178283-A | 2-phenyl-2, 3-dihydro-quinazolin-4 (1H) -one derivative, preparation and application thereof | 武汉科技大学 | 2023-05-30 | — | — | CN | disclosed |