Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 7/20 | 1.00 |
| ▸ | EGFR | P00533 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 3/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29010778 | 0.91 | TNKS2 (0.83) | TNKS2EGFRMAPTGAAKMT2A | |
| SCHEMBL29010896 | 0.91 | TNKS2 (0.83) | TNKS2EGFRMAPTGAAKMT2A | |
| SCHEMBL29010891 | 0.91 | TNKS2 (0.83) | TNKS2EGFRMAPTGAAKMT2A | |
| SCHEMBL29010775 | 0.91 | TNKS2 (0.83) | TNKS2EGFRMAPTGAAKMT2A | |
| SCHEMBL29010909 | 0.88 | TNKS2 (0.78) | TNKS2EGFRMAPTGAAKMT2A | |
| SCHEMBL29010783 | 0.86 | TNKS2 (1.00) | TNKS2EGFRMAPTKMT2AKDM4E | |
| SCHEMBL8252630 | 0.81 | TNKS2 (0.67) | TNKS2GRM5MAOAMAOB | |
| SCHEMBL5248973 | 0.76 | TNKS2 (1.00) | TNKS2MAPTGAAKMT2AKDM4E | |
| SCHEMBL29913499 | 0.76 | TNKS2 (1.00) | TNKS2MAPTGAAKMT2AKDM4E | |
| SCHEMBL6124226 | 0.76 | TNKS2 (0.73) | TNKS2MAPTGAAKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178283-B | 2-Phenyl-2, 3-dihydro-quinazolin-4 (1H) -one derivative, preparation and application thereof | 武汉科技大学 | 2024-07-02 | — | — | CN | disclosed |
| CN-116178283-A | 2-phenyl-2, 3-dihydro-quinazolin-4 (1H) -one derivative, preparation and application thereof | 武汉科技大学 | 2023-05-30 | — | — | CN | disclosed |