Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.39 |
| ▸ | CNR1 | P21554 | 3/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22572569 | 0.83 | ALDH1A1 (0.44) | CNR2CNR1ALDH1A1 | |
| SCHEMBL29011012 | 0.80 | ALDH1A1 (0.36) | CNR2CNR1BRAFALDH1A1 | |
| SCHEMBL29011022 | 0.78 | ALDH1A1 (0.34) | BRAFALDH1A1 | |
| SCHEMBL29010898 | 0.76 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL29011042 | 0.72 | CNR1 (0.31) | CNR2CNR1 | |
| SCHEMBL15881089 | 0.71 | HCAR2 (0.46) | ALDH1A1 | |
| SCHEMBL1012771 | 0.71 | CNR2 (0.37) | CNR2CNR1ALDH1A1 | |
| SCHEMBL25793266 | 0.69 | CNR2 (0.56) | CNR2CNR1BRAFALDH1A1 | |
| SCHEMBL20320548 | 0.69 | CNR2 (0.38) | CNR2CNR1ALDH1A1 | |
| SCHEMBL28826166 | 0.68 | CYP1A2 (0.35) | BRAFALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116075513-A | Inhibitors of NEK7 kinase | 哈利亚治疗公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-115843272-A | Inhibitors of NEK7 kinase | 哈利亚治疗公司 | 2023-03-24 | — | — | CN | disclosed |