Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23144219 | 0.77 | FGFR1 (0.35) | L3MBTL1CHRNA7ATMALDH1A1MAPT | |
| SCHEMBL28826217 | 0.75 | L3MBTL1 (0.49) | CYP1A2L3MBTL1CYP2C19ALDH1A1MAPT | |
| SCHEMBL23144179 | 0.75 | CHEK1 (0.38) | BRAFDHODH | |
| SCHEMBL29065136 | 0.73 | CHRNA7 (0.43) | CHRNA7BRAFCYP2C19ELANEMTOR | |
| SCHEMBL23155782 | 0.72 | ABL1 (0.38) | BRAFALDH1A1EGFRDHODH | |
| SCHEMBL23144302 | 0.71 | FTO (0.42) | CYP2C19ALDH1A1MAPTFGFR1FGFR4 | |
| SCHEMBL29811955 | 0.71 | FTO (0.42) | CYP2C19ALDH1A1MAPTFGFR1FGFR4 | |
| SCHEMBL28826091 | 0.69 | KDM4E (0.36) | CYP1A2HPGDCYP2C19ALDH1A1PDE4B | |
| SCHEMBL29212362 | 0.69 | CYP1A2 (0.34) | CYP1A2L3MBTL1HPGDCYP2C19ALDH1A1 | |
| SCHEMBL29010902 | 0.68 | CNR2 (0.39) | BRAFALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115003299-A | Methods and compounds for restoring function of mutant p53 | 皮姆维制药公司 | 2022-09-02 | — | — | CN | disclosed |