Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 5/20 | 0.31 |
| ▸ | CNR1 | P21554 | 4/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29011022 | 0.88 | ALDH1A1 (0.34) | ALDH1A1MAPK14KIF11BRAF | |
| SCHEMBL29010898 | 0.87 | ALDH1A1 (0.39) | ALDH1A1MAPK14KIF11EPHX2MEN1 | |
| SCHEMBL22572569 | 0.87 | ALDH1A1 (0.44) | ALDH1A1MAPK14CNR2CNR1MEN1 | |
| SCHEMBL29010902 | 0.80 | CNR2 (0.39) | ALDH1A1CNR2CNR1BRAF | |
| SCHEMBL29011042 | 0.76 | CNR1 (0.31) | CNR2CNR1 | |
| SCHEMBL15881089 | 0.74 | HCAR2 (0.46) | ALDH1A1MEN1KMT2A | |
| SCHEMBL29011020 | 0.70 | EPHX2 (0.35) | EPHX2MEN1KMT2A | |
| SCHEMBL29010906 | 0.70 | LMNA (0.43) | ALDH1A1MAPK14EPHX2MEN1KMT2A | |
| SCHEMBL29011027 | 0.70 | BACE1 (0.32) | — | |
| SCHEMBL29011046 | 0.70 | NEK7 (0.32) | ALDH1A1KIF11MEN1KMT2ABRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115843272-A | Inhibitors of NEK7 kinase | 哈利亚治疗公司 | 2023-03-24 | — | — | CN | disclosed |