Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.55 |
| ▸ | GSK3B | P49841 | 1/20 | 0.55 |
| ▸ | CCR6 | P51684 | 1/20 | 0.55 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylcyclopentane SCHEMBL29010800 | 0.93 | GSK3A (0.52) | GSK3AGSK3BCCR6CRBNCA1 | |
| SCHEMBL29010973 | 0.91 | GSK3A (0.50) | GSK3AGSK3BCCR6CRBNCA1 | |
| SCHEMBL4938638 | 0.91 | GSK3A (0.50) | GSK3AGSK3BCCR6CRBNCA1 | |
| SCHEMBL29010798 | 0.91 | GSK3A (0.50) | GSK3AGSK3BCCR6CRBNCA1 | |
| SCHEMBL29010933 | 0.90 | GSK3A (0.61) | GSK3AGSK3BCCR6CRBNBRD4 | |
| Bicarbonate SCHEMBL9841170 | 0.83 | GSK3A (0.42) | GSK3AGSK3BCCR6CRBNCA1 | |
| SCHEMBL11596092 | 0.78 | GSK3A (0.79) | GSK3AGSK3BCCR6CRBN | |
| Cyclohexane SCHEMBL28392500 | 0.78 | GSK3A (0.79) | GSK3AGSK3BCCR6CRBN | |
| Cyclopentane SCHEMBL29123251 | 0.78 | GSK3A (0.79) | GSK3AGSK3BCCR6CRBN | |
| Cyclohexane SCHEMBL19996052 | 0.78 | GSK3A (0.79) | GSK3AGSK3BCCR6CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116199747-A | Lidamycin prodrug, preparation method and application thereof in preparation of antitumor drugs | 中国医学科学院医药生物技术研究所 | 2023-06-02 | — | — | CN | disclosed |