SCHEMBL29010933

SCHEMBL29010933

CC1CC1.O=C1C=CC(=O)N1

nearest known ligand 0.61

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 1/20 0.61
GSK3B P49841 1/20 0.61
CCR6 P51684 1/20 0.61
CRBN Q96SW2 1/20 0.42
BRD4 O60885 1/20 0.32
CREBBP Q92793 1/20 0.32
TLR4 O00206 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29010977 0.90 GSK3A (0.55) GSK3AGSK3BCCR6CRBNBRD4
Methylcyclopentane SCHEMBL29010800 0.87 GSK3A (0.52) GSK3AGSK3BCCR6CRBN
SCHEMBL29010973 0.85 GSK3A (0.50) GSK3AGSK3BCCR6CRBN
SCHEMBL29010798 0.85 GSK3A (0.50) GSK3AGSK3BCCR6CRBN
SCHEMBL4938638 0.85 GSK3A (0.50) GSK3AGSK3BCCR6CRBN
SCHEMBL316039 0.82 GSK3A (0.41) GSK3AGSK3BCCR6
SCHEMBL4635968 0.80 GSK3A (0.50) GSK3AGSK3BCCR6CRBNBRD4
Propylene Oxide SCHEMBL11351469 0.79 GSK3A (0.55) GSK3AGSK3BCCR6CRBNBRD4
Bicarbonate SCHEMBL9841170 0.79 GSK3A (0.42) GSK3AGSK3BCCR6CRBN
Ethane SCHEMBL11390749 0.78 GSK3A (0.85) GSK3AGSK3BCCR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116199747-A Lidamycin prodrug, preparation method and application thereof in preparation of antitumor drugs 中国医学科学院医药生物技术研究所 2023-06-02 CN disclosed