Hydrazine

Hydrazine

SCHEMBL29011024

NN.Nc1nc(N)c2ccccc2n1.S=C[S-].S=C[S-].[Pt+2]

nearest known ligand 0.72

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DCPS Q96C86 1/20 0.72
DHFR P00374 4/20 0.50
NUDT1 P36639 2/20 0.49
ALDH1A1 P00352 2/20 0.49
HPGD P15428 2/20 0.49
HSD17B10 Q99714 2/20 0.49
CYP1A2 P05177 1/20 0.49
ADORA2A P29274 5/20 0.47
SMN1; SMN2 Q16637 2/20 0.42
NPC1 O15118 1/20 0.42
TP53 P04637 1/20 0.42
PKM P14618 1/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
NFKB1 P19838 1/20 0.42
MAPK1 P28482 1/20 0.42
RAB9A P51151 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrazine SCHEMBL29011033 0.85 DCPS (0.91) DCPSDHFRNUDT1ALDH1A1HPGD
SCHEMBL269636 0.85 DCPS (1.00) DCPSDHFRNUDT1ALDH1A1HPGD
SCHEMBL29375878 0.85 DCPS (1.00) DCPSDHFRNUDT1ALDH1A1HPGD
Hydrochloric Acid SCHEMBL27786605 0.83 DCPS (0.95) DCPSDHFRNUDT1ALDH1A1HPGD
Hydrochloric Acid SCHEMBL6601650 0.83 DCPS (0.95) DCPSDHFRNUDT1ALDH1A1HPGD
SCHEMBL30468763 0.83 DCPS (0.95) DCPSDHFRNUDT1ALDH1A1HPGD
SCHEMBL29011023 0.76 DCPS (0.62) DCPSDHFRNUDT1ALDH1A1HPGD
Pyrrole SCHEMBL5652472 0.69 DCPS (0.66) DCPSDHFRNUDT1ALDH1A1HPGD
SCHEMBL9605513 0.67 DHFR (1.00) DCPSDHFRNUDT1ADORA2AHRH4
SCHEMBL12545043 0.67 PDE5A (0.59) DCPSDHFRALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113845548-B Platinum complex of quinazoline hydrazine dithioformate and preparation method and application thereof 深圳大学 2023-06-06 CN disclosed