Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCPS | Q96C86 | 1/20 | 0.66 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL269636 | 0.81 | DCPS (1.00) | DCPSNUDT1HSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL29375878 | 0.81 | DCPS (1.00) | DCPSNUDT1HSD17B10ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL6601650 | 0.79 | DCPS (0.95) | DCPSNUDT1HSD17B10ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL27786605 | 0.79 | DCPS (0.95) | DCPSNUDT1HSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL30468763 | 0.79 | DCPS (0.95) | DCPSNUDT1HSD17B10ALDH1A1CYP1A2 | |
| Hydrazine SCHEMBL29011033 | 0.77 | DCPS (0.91) | DCPSNUDT1HSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL561316 | 0.71 | ADORA3 (0.64) | DCPSNUDT1HSD17B10ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL14842653 | 0.70 | DCPS (0.53) | DCPSHSD17B10ALDH1A1CYP1A2HPGD | |
| SCHEMBL3088381 | 0.69 | ADORA3 (0.66) | DCPSNUDT1HSD17B10ALDH1A1CYP1A2 | |
| Hydrazine SCHEMBL29011024 | 0.69 | DCPS (0.72) | DCPSNUDT1HSD17B10ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7253177-B2 | Synthesis and antimalarial activity of pyrrolo[3,2-f]quinazoline-1,3-diamine derivatives | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2007-08-07 | — | — | US | disclosed |
| WO-2006046949-A1 | SYNTHESIS AND ANTIMALARIAL ACTIVITY OF PYRROLO[3,2-f]QUINAZOLINE-1,3- DIAMINE DERIVATIVES | WALTER REED ARMY INSTITUTE OF RESEARCH (WRAIR) (US) | 2006-05-04 | — | — | WO | disclosed |
| US-20060094736-A1 | Synthesis and antimalarial activity of pyrrolo[3,2-f]quinazoline-1,3-diamine derivatives | ARMY, UNITED STATES | 2006-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094736-A1 | Synthesis and antimalarial activity of pyrrolo[3,2-f]quinazoline-1,3-diamine derivatives | CPS1, PADI1, ALDH18A1 | DCPS 1502/4885NUDT1 380/4885HSD17B10 1538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.