Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.93 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL904375 | 0.97 | TLR7 (1.00) | TLR7 | |
| Pyrophosphoric Acid SCHEMBL2899330 | 0.96 | TLR7 (0.89) | TLR7 | |
| SCHEMBL2901496 | 0.94 | TLR7 (0.95) | TLR7 | |
| SCHEMBL2849235 | 0.94 | TLR7 (1.00) | TLR7 | |
| Succinic Acid SCHEMBL2898930 | 0.93 | TLR7 (0.92) | TLR7 | |
| Succinic Acid SCHEMBL2901412 | 0.93 | TLR7 (0.92) | TLR7 | |
| Fumaric Acid SCHEMBL2902019 | 0.92 | TLR7 (0.90) | TLR7 | |
| Fumaric Acid SCHEMBL2902017 | 0.92 | TLR7 (0.90) | TLR7 | |
| SCHEMBL2848225 | 0.91 | TLR7 (1.00) | TLR7 | |
| Benzoic Acid SCHEMBL2901421 | 0.90 | TLR7 (0.88) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2435412-B1 | SACCHARIN, FUMARIC ACID, 1-HYDROXY-2-NAPHTHOIC ACID AND BENZOIC ACID SALTS OF 4-(DIMETHYLAMINO)BUTYL 2-(4-((2-AMINO-4-METHYL-6-(PENTYLAMINO)PYRIMIDIN-5-YL)METHYL)PHENYL)ACETATE | ASTRAZENECA AB (SE) | 2016-01-27 | — | — | EP | disclosed |
| US-8476288-B2 | Salts 756 | ASTRAZENECA AB (SE) | 2013-07-02 | — | — | US | disclosed |
| WO-2010133882-A1 | DISACCHARIN, DIFUMARIC ACID, DI-L-HYDROXY-2-NAPHTHOIC ACID AND MONO-BENZOIC ACID SALTS OF 4- (DIMETHYLAMIN0)BUTYL 2- (4- ( (2-AMINO-4-METHYL-6- (PENTYLAMINO) PYRIMIDIN- 5 -YL) METHYL) PHENYL)ACETATE | ASTRAZENECA AB (SE) | 2010-11-25 | — | — | WO | disclosed |
| US-20100298364-A1 | SALTS 756 | ASTRAZENECA AB (SE) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298364-A1 | SALTS 756 | SLC10A6, SLC10A1, SLC6A6 | TLR7 1895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.