Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20886292 | 1.00 | LMNA (0.50) | LMNATHRBMEN1CYP1A2KMT2A | |
| SCHEMBL29012739 | 1.00 | LMNA (0.50) | LMNATHRBMEN1CYP1A2KMT2A | |
| SCHEMBL11546616 | 0.77 | LMNA (0.42) | LMNATHRB | |
| SCHEMBL9998684 | 0.73 | — | — | |
| SCHEMBL289118 | 0.73 | — | — | |
| SCHEMBL27803886 | 0.73 | THRB (0.44) | LMNATHRBMEN1CYP1A2KMT2A | |
| SCHEMBL27471022 | 0.72 | LMNA (0.56) | LMNATHRB | |
| SCHEMBL6679881 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL9998583 | 0.71 | DNM1 (0.52) | LMNATHRBMEN1CYP1A2KMT2A | |
| Hydrochloric Acid SCHEMBL8836548 | 0.71 | THRB (0.42) | LMNATHRBMEN1CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111417630-B | Modulators of interferon gene stimulating factor (STING) | 葛兰素史克知识产权开发有限公司 | 2023-06-06 | — | — | CN | disclosed |