Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.56 |
| ▸ | CA2 | P00918 | 4/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27975121 | 0.86 | CA1 (0.51) | CA1CA2GAAKMT2AMEN1 | |
| SCHEMBL28507827 | 0.86 | CA1 (0.62) | CA1CA2CA14KMT2ABIRC2 | |
| SCHEMBL30475458 | 0.85 | CA2 (0.54) | CA1CA2CA12CA14GAA | |
| SCHEMBL28610755 | 0.85 | CA1 (0.49) | CA1CA2CA12CA14GAA | |
| SCHEMBL27705382 | 0.85 | CA2 (0.48) | CA1CA2GAAKMT2AMEN1 | |
| SCHEMBL27933679 | 0.84 | CA2 (0.53) | CA1CA2CA12CA14GAA | |
| SCHEMBL27622585 | 0.83 | CA2 (0.61) | CA1CA2CA12CA14GAA | |
| SCHEMBL29147476 | 0.81 | CA2 (0.44) | CA1CA2GAAKMT2AMEN1 | |
| SCHEMBL21052458 | 0.80 | CA2 (0.75) | CA1CA2GAAKMT2ABIRC2 | |
| SCHEMBL29282254 | 0.79 | HDAC1 (0.38) | CA1CA2GAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116261458-B | PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2024-05-24 | — | — | CN | disclosed |
| CN-116261458-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2023-06-13 | — | — | CN | disclosed |