Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29013161 | 0.92 | CA2 (0.52) | CA2MAPK1MEN1GAAKMT2A | |
| SCHEMBL29147480 | 0.90 | CA2 (0.50) | CA2MAPK1MEN1GAAKMT2A | |
| SCHEMBL29282532 | 0.88 | CHRM1 (0.53) | CA2MAPK1MEN1GAAKMT2A | |
| SCHEMBL28560543 | 0.87 | CA2 (0.50) | CA2MAPK1MEN1GAAKMT2A | |
| SCHEMBL29013172 | 0.85 | CA1 (0.56) | CA2MEN1GAAKMT2ACA1 | |
| SCHEMBL29264683 | 0.81 | CA2 (0.43) | CA2MAPK1MEN1GAAKMT2A | |
| SCHEMBL21281735 | 0.81 | CA2 (0.37) | CA2MAPK1MEN1GAAKMT2A | |
| SCHEMBL29282254 | 0.81 | HDAC1 (0.38) | CA2MEN1GAAKMT2ACA1 | |
| SCHEMBL27555803 | 0.80 | ACE2 (0.35) | CA2MEN1GAAKMT2ACA1 | |
| SCHEMBL28507828 | 0.80 | CA2 (0.48) | CA2MAPK1KMT2ACA1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118019750-A | Drug delivery system for local delivery of therapeutic agents and uses thereof | 上海椿安生物医药科技有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-101035790-B | (1S,5S) -3- (5, 6-dichloropyridin-3-yl) -3, 6-diazabicyclo [3.2.0] heptane benzenesulfonate | ABBOTT LAB | 2012-09-26 | — | — | CN | disclosed |
| CN-101035790-A | (1S,5S) -3- (5, 6-dichloropyridin-3-yl) -3, 6-diazabicyclo [3.2.0] heptane benzenesulfonate | ABBOTT LAB (US) | 2007-09-12 | — | — | CN | disclosed |