Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.57 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22453750 | 0.80 | CYP4F2 (0.44) | CYP4F2CYP4A11GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL69660 | 0.79 | CYP4F2 (0.86) | CYP4F2CYP4A11GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL887264 | 0.77 | NPC1 (0.59) | GAAALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL30146895 | 0.77 | NPC1 (0.59) | GAAALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL14717838 | 0.77 | SIRT2 (0.45) | GAAALDH1A1SMN1; SMN2RAB9ATDP1 | |
| SCHEMBL28290543 | 0.76 | MAPT (0.51) | GAAALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL28008696 | 0.76 | CYP4F2 (0.81) | CYP4F2CYP4A11GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL15324634 | 0.76 | HTT (0.50) | POLBGAAALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL11636131 | 0.75 | MAPT (0.50) | GAASMN1; SMN2NPC1RAB9ATDP1 | |
| SCHEMBL13948404 | 0.75 | CYP4F2 (0.73) | CYP4F2CYP4A11GAAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115043736-B | Method for preparing nitrogen-containing aryl compound by using nitrogen-containing and protecting group compounds | 苏州大学 | 2024-08-30 | — | — | CN | disclosed |
| CN-115043736-A | Method for preparing nitrogen-containing aryl compound by using nitrogen-containing and protecting group compound | 苏州大学 | 2022-09-13 | — | — | CN | disclosed |