SCHEMBL887264

SCHEMBL887264

CCc1ccccc1Nc1ccc(C)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.59
RAB9A P51151 2/20 0.59
GAA P10253 3/20 0.56
MAPT P10636 3/20 0.56
TDP1 Q9NUW8 1/20 0.56
HPGD P15428 1/20 0.52
HTT P42858 1/20 0.45
EGFR P00533 1/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
ALDH1A1 P00352 2/20 0.43
PTGS2 P35354 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
GRIN2D O15399 1/20 0.42
GRIN3B O60391 1/20 0.42
GRIN1 Q05586 1/20 0.42
GRIN2A Q12879 1/20 0.42
GRIN2B Q13224 1/20 0.42
GRIN2C Q14957 1/20 0.42
GRIN3A Q8TCU5 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30146895 1.00 NPC1 (0.59) NPC1RAB9AGAAMAPTTDP1
SCHEMBL14320839 0.92 HTT (0.50) NPC1RAB9AGAAMAPTTDP1
SCHEMBL4544842 0.87 KCNH3 (0.50) NPC1RAB9AGAAMAPTTDP1
SCHEMBL3148744 0.86 MEN1 (0.48) NPC1RAB9AGAAMAPTHTT
SCHEMBL29657744 0.86 MAPT (0.50) NPC1RAB9AGAAMAPTTDP1
SCHEMBL6029657 0.86 MAPT (0.50) NPC1RAB9AGAAMAPTTDP1
SCHEMBL23846636 0.83 HTT (0.44) NPC1RAB9AGAAMAPTHTT
SCHEMBL11347170 0.83 MAPT (0.58) RAB9AGAAMAPTTDP1HPGD
SCHEMBL31310663 0.83 POLB (0.47) NPC1RAB9AGAAMAPTHTT
SCHEMBL20351918 0.83 HTT (0.64) NPC1RAB9AGAAMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11067909-B2 Terphenyl compound, electrophotographic photosensitive member, and method for producing terphenyl compound KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2021-07-20 US disclosed
US-11003101-B2 Electrophotographic photosensitive member, process cartridge, and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2021-05-11 US disclosed
US-10996575-B2 Electrophotographic photosensitive member, process cartridge, and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2021-05-04 US disclosed
US-20200233324-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2020-07-23 US disclosed
US-20200233323-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2020-07-23 US disclosed
US-20200231535-A1 TERPHENYL COMPOUND, ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, AND METHOD FOR PRODUCING TERPHENYL COMPOUND KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2020-07-23 US disclosed
US-7863227-B2 High performance lubricant containing high molecular weight aromatic amine antioxidant and low boron content dispersant EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2011-01-04 US disclosed
US-20070232504-A1 High performance lubricant containing high molecular weight aromatic amine antioxidant and low boron content dispersant EXXONMOBIL RESEARCH AND ENGINEERING 2007-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11067909-B2 Terphenyl compound, electrophotographic photosensitive member, and method for producing terphenyl compound ABCB1, TERB1, PAH NPC1 467/4885RAB9A 937/4885GAA 2625/4885
US-20200231535-A1 TERPHENYL COMPOUND, ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, AND METHOD FOR PRODUCING TERPHENYL COMPOUND ABCB1, TERB1, PAH NPC1 467/4885RAB9A 937/4885GAA 2625/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.