SCHEMBL29013720

SCHEMBL29013720

Cc1c[c]c2ncccc2n1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
CYP1A2 P05177 2/20 0.36
PRMT5 O14744 1/20 0.36
PDK1 Q15118 1/20 0.34
HSP90AA1 P07900 2/20 0.32
NOS3 P29474 1/20 0.32
NOS1 P29475 1/20 0.32
NOS2 P35228 1/20 0.32
NPC1 O15118 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
KDM4E B2RXH2 3/20 0.32
LMNA P02545 2/20 0.32
NCF1 P14598 1/20 0.32
TGFBR1 P36897 1/20 0.31
MAPT P10636 2/20 0.31
CCR1 P32246 2/20 0.31
CCR8 P51685 2/20 0.31
GMNN O75496 1/20 0.31
TP53 P04637 1/20 0.31
MMP2 P08253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL96433 0.69 CYP1A2 (0.45) ALDH1A1CYP1A2KDM4ENCF1MAPT
SCHEMBL7467848 0.69 ALDH1A1 (0.33) ALDH1A1KDM4ELMNAMAPT
SCHEMBL4409649 0.69 ALDH1A1 (0.48) ALDH1A1CYP1A2HSP90AA1NPC1L3MBTL1
SCHEMBL7972525 0.69 CYP1A2 (0.41) ALDH1A1CYP1A2NPC1NCF1
SCHEMBL30464282 0.67 CYP1A2 (0.52) ALDH1A1CYP1A2HSP90AA1NPC1KDM4E
SCHEMBL10851 0.67 ALDH1A1 (0.44) ALDH1A1CYP1A2PDK1HSP90AA1NPC1
SCHEMBL195915 0.67 CYP1A2 (0.52) ALDH1A1CYP1A2HSP90AA1NPC1KDM4E
SCHEMBL5926098 0.64 PARP1 (0.37) ALDH1A1CYP1A2NPC1KDM4ELMNA
SCHEMBL286948 0.64 ALDH1A1 (0.37) ALDH1A1CYP1A2PDK1NPC1L3MBTL1
SCHEMBL2629404 0.64 BCHE (0.42) ALDH1A1CYP1A2PRMT5CCR1CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112638997-B Film and packaging container 住友化学株式会社 2023-04-28 CN disclosed