SCHEMBL7972525

SCHEMBL7972525

Cc1cnc2[c]cccc2n1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 6/20 0.41
NPC1 O15118 1/20 0.33
PKM P14618 1/20 0.33
RAB9A P51151 1/20 0.33
CCNB2 O95067 1/20 0.33
CDK1 P06493 1/20 0.33
CCNB1 P14635 1/20 0.33
CDK5 Q00535 1/20 0.33
CDK5R1 Q15078 1/20 0.33
CCNB3 Q8WWL7 1/20 0.33
NCF1 P14598 1/20 0.32
CYP2A6 P11509 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HTR3A P46098 1/20 0.30
HRH4 Q9H3N8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7271710 0.85 CYP1A2 (0.37) CYP1A2NPC1PKMRAB9ACCNB2
SCHEMBL4843376 0.77 BACE1 (0.36) NCF1ALDH1A1
SCHEMBL4843280 0.77 BCHE (0.30)
SCHEMBL7976285 0.77 ALDH1A1 (0.37) NPC1RAB9AALDH1A1
SCHEMBL1789932 0.74 NPC1 (0.46) CYP1A2NPC1RAB9AALDH1A1
SCHEMBL4573051 0.74 GPR3 (0.39) CYP1A2ALDH1A1HRH4
SCHEMBL28571 0.70 PDE10A (0.52) CYP1A2NPC1RAB9ACCNB2CDK1
SCHEMBL426806 0.69 CYP1A2 (0.50) CYP1A2RAB9ANCF1ALDH1A1
SCHEMBL29013720 0.69 ALDH1A1 (0.39) CYP1A2NPC1NCF1ALDH1A1
SCHEMBL2889003 0.69 CYP1A2 (0.50) CYP1A2CYP2A6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6268514-B1 TREATING INDUSTRIAL MATERIALS WITH NITROETHANE COMPOUND FOR PROTECTING AGAINST ATTACK AND DESTRUCTION BY MICROORGANISMS BASF AKTIENGESELLSCHAFT (DE) 2001-07-31 US disclosed