Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | SUMO3 | P55854 | 1/20 | 0.32 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.32 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoline SCHEMBL11076491 | 0.70 | ALDH1A1 (0.55) | ALDH1A1KDM4EMEN1KMT2APDE10A | |
| SCHEMBL29013720 | 0.69 | ALDH1A1 (0.39) | ALDH1A1KDM4ELMNAMAPT | |
| Quinoline SCHEMBL27518259 | 0.68 | ALDH1A1 (0.57) | ALDH1A1KDM4EPDE4APDE4CPDE4D | |
| SCHEMBL989154 | 0.66 | PDE10A (0.62) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL251828 | 0.64 | — | — | |
| SCHEMBL30043754 | 0.64 | — | — | |
| SCHEMBL322184 | 0.64 | CYSLTR1 (0.49) | LMNAPDE10A | |
| SCHEMBL167042 | 0.64 | ALDH1A1 (0.47) | ALDH1A1KDM4EPDE4APDE4CPDE4D | |
| Ammonia Solution, Strong SCHEMBL230642 | 0.63 | HRH1 (0.47) | ALDH1A1SUMO3SUMO2SUMO1LMNA | |
| Iodide SCHEMBL11396772 | 0.63 | HRH1 (0.47) | ALDH1A1SUMO3SUMO2SUMO1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993016071-A1 | HETEROCYCLIC DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-19 | — | — | WO | disclosed |