SCHEMBL2901415

SCHEMBL2901415

CCO[Si](Cc1ccccc1[S])(OCC)OCC

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31
MAPT P10636 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8142412 0.78 TAAR1 (0.41) MAPT
SCHEMBL19809277 0.77 HSPA5 (0.45)
SCHEMBL6473234 0.77 ALDH1A1 (0.42) MAPTNPSR1L3MBTL1
SCHEMBL1963873 0.77 IDO1 (0.42) MAPTL3MBTL1
SCHEMBL1971325 0.76 L3MBTL1 (0.53) MAPTNPSR1L3MBTL1
SCHEMBL1974352 0.76 IDO1 (0.47) MAPTL3MBTL1
SCHEMBL2817172 0.74 CYP1A2 (0.46) MAPT
SCHEMBL29975060 0.74 CYP1A2 (0.46) MAPT
SCHEMBL2812125 0.73 ALDH1A1 (0.34)
SCHEMBL13027305 0.72 ESR1 (0.37) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2213477-A1 Rubber composition and tire The Goodyear Tire & Rubber Company (US) 2010-08-04 EP claimed
EP-2213477-A1 Rubber composition and tire The Goodyear Tire & Rubber Company (US) 2010-08-04 EP disclosed