Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31517138 | 0.88 | KCNH2 (0.42) | KCNH2GPR84HCAR2PPARAHCAR3 | |
| Sulfuric Acid SCHEMBL28590458 | 0.83 | HCAR3 (0.33) | KCNH2HCAR2HCAR3MAPT | |
| Sulfuric Acid SCHEMBL27760045 | 0.82 | KCNH2 (0.42) | KCNH2GPR84HCAR2PPARAHCAR3 | |
| Sulfuric Acid SCHEMBL27781376 | 0.75 | NOS2 (0.37) | KCNH2HCAR2PPARAHCAR3MAPT | |
| Trifluoromethanesulfonic Acid SCHEMBL28593178 | 0.74 | EPHX1 (0.30) | HCAR2HCAR3 | |
| SCHEMBL10864659 | 0.73 | KCNH2 (0.48) | KCNH2GPR84HCAR2PPARAHCAR3 | |
| SCHEMBL30191371 | 0.73 | KCNH2 (0.48) | KCNH2GPR84HCAR2PPARAHCAR3 | |
| Acetic Acid SCHEMBL28946334 | 0.71 | KCNH2 (0.47) | KCNH2GPR84HCAR2PPARAHCAR3 | |
| SCHEMBL7579081 | 0.71 | KCNH2 (0.43) | KCNH2GPR84HCAR2PPARAHCAR3 | |
| SCHEMBL10697416 | 0.71 | KCNH2 (0.50) | KCNH2GPR84MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114606508-B | Environment-friendly ionic liquid degreasing fluid and application method thereof | 四川大学 | 2023-06-06 | — | — | CN | disclosed |