Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 12/20 | 0.49 |
| ▸ | ALKBH2 | Q6NS38 | 2/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.38 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12496800 | 0.85 | ACHE (0.51) | ACHEALKBH2HPGDSL3MBTL1EGLN1 | |
| SCHEMBL27499937 | 0.84 | ACHE (0.47) | ACHEEGLN1 | |
| SCHEMBL20138448 | 0.84 | ACHE (0.51) | ACHEL3MBTL1 | |
| Hydrochloric Acid SCHEMBL29715821 | 0.83 | ACHE (0.50) | ACHEALKBH2HPGDSL3MBTL1EGLN1 | |
| SCHEMBL4238168 | 0.80 | ACHE (0.48) | ACHE | |
| SCHEMBL2057002 | 0.77 | ACHE (0.66) | ACHEALKBH2HPGDSL3MBTL1EGLN1 | |
| SCHEMBL15155186 | 0.76 | ALKBH2 (0.50) | ACHEALKBH2HPGDSL3MBTL1EGLN1 | |
| SCHEMBL29014777 | 0.76 | ACHE (0.48) | ACHE | |
| SCHEMBL29014786 | 0.76 | ACHE (0.44) | ACHE | |
| SCHEMBL35210101 | 0.75 | ACHE (0.57) | ACHEALKBH2HPGDSL3MBTL1EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116056697-A | 2-oxo-oxazolidine-5-carboxamides as NAV1.8 inhibitors | 默沙东有限责任公司 | 2023-05-02 | — | — | CN | disclosed |