Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.44 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20138448 | 0.78 | ACHE (0.51) | ACHE | |
| SCHEMBL369320 | 0.76 | MLYCD (0.43) | MLYCDRAB9ASMN1; SMN2 | |
| SCHEMBL29014753 | 0.76 | ACHE (0.49) | ACHE | |
| SCHEMBL27499937 | 0.74 | ACHE (0.47) | ACHE | |
| SCHEMBL25153713 | 0.74 | LMNA (0.47) | ACHEMLYCDTP53GPR119 | |
| SCHEMBL29014777 | 0.73 | ACHE (0.48) | ACHESMN1; SMN2 | |
| SCHEMBL24124350 | 0.73 | MLYCD (0.48) | ACHEMLYCDGPR119 | |
| SCHEMBL15287393 | 0.73 | MLYCD (0.43) | ACHEMLYCDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4238168 | 0.71 | ACHE (0.48) | ACHE | |
| SCHEMBL30882598 | 0.70 | RAB9A (0.43) | MLYCDNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116056697-A | 2-oxo-oxazolidine-5-carboxamides as NAV1.8 inhibitors | 默沙东有限责任公司 | 2023-05-02 | — | — | CN | disclosed |