SCHEMBL29015263

SCHEMBL29015263

CC(C)Cn1c(N)nc(=O)c2[nH]cnc21

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 12/20 0.61
ADORA2B P29275 8/20 0.61
PNP P00491 1/20 0.59
PDE4A P27815 10/20 0.58
PDE4B Q07343 10/20 0.58
PDE4C Q08493 10/20 0.58
PDE4D Q08499 10/20 0.58
CFTR P13569 2/20 0.58
PDE2A O00408 2/20 0.58
PDE1A P54750 2/20 0.58
PDE1B Q01064 2/20 0.58
PDE1C Q14123 2/20 0.58
ADORA1 P30542 2/20 0.58
PDE3A Q14432 2/20 0.58
PDE5A O76074 1/20 0.58
CYP1A2 P05177 1/20 0.58
CYP3A4 P08684 1/20 0.58
TSHR P16473 1/20 0.58
MAPK1 P28482 1/20 0.58
SCN1A P35498 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1-Methylxanthine SCHEMBL29015259 0.85 ADORA2A (0.57) ADORA2AADORA2BPNPPDE4APDE4B
SCHEMBL6035390 0.83 PNP (0.63) ADORA2AADORA2BPNPPDE4APDE4B
SCHEMBL29015261 0.78 ADORA2A (0.46) ADORA2AADORA2BPNPPDE4APDE4B
SCHEMBL5504400 0.78 ADORA2A (0.59) ADORA2AADORA2BPNPPDE4APDE4B
SCHEMBL563300 0.77 ADORA2B (0.63) ADORA2AADORA2BPNPPDE4APDE4B
SCHEMBL5667530 0.77 ADORA2A (0.61) ADORA2AADORA2BPNPPDE4APDE4B
SCHEMBL6310571 0.75 ADORA2A (0.70) ADORA2AADORA2BPNPPDE4APDE4B
SCHEMBL48434 0.74 ATAD2 (0.54) ADORA2AADORA2BPNPPDE4APDE4B
SCHEMBL16494563 0.74 PNP (0.52) ADORA2AADORA2BPNPPDE4APDE4B
Isobutylmethylxanthine SCHEMBL7637581 0.74 PDE4A (0.94) ADORA2AADORA2BPDE4APDE4BPDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116096860-A Mammalian livestock pluripotent stem cell line from delayed embryo 阿塞尔塔有限公司 2023-05-09 CN disclosed