Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 2/20 | 0.33 |
| ▸ | POLQ | O75417 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | PLK4 | O00444 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | FLT4 | P35916 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17589968 | 0.84 | PIK3CG (0.33) | PIK3CGDYRK1APTGDR2PIM1POLQ | |
| SCHEMBL290811 | 0.84 | PAX8 (0.40) | PIK3CGDYRK1APIM1POLQTRPM8 | |
| SCHEMBL17641123 | 0.78 | PIK3CG (0.37) | PIK3CGDYRK1APTGDR2HCAR2PIM1 | |
| SCHEMBL17641124 | 0.76 | PIK3CG (0.40) | PIK3CGDYRK1APTGDR2HCAR2POLQ | |
| SCHEMBL13074524 | 0.75 | HCAR2 (0.37) | PIK3CGDYRK1APTGDR2HCAR2PIM1 | |
| SCHEMBL13079071 | 0.75 | — | — | |
| SCHEMBL17589770 | 0.74 | CYP11B1 (0.38) | PIK3CGDYRK1APIM1CYP3A4CYP11B2 | |
| SCHEMBL13047486 | 0.73 | TRPM8 (0.36) | PIK3CGDYRK1APTGDR2POLQTRPM8 | |
| SCHEMBL18569311 | 0.73 | APP (0.35) | PIK3CGDYRK1APTGDR2PIM1CYP3A4 | |
| SCHEMBL13048433 | 0.72 | PAX8 (0.42) | PIK3CGDYRK1APTGDR2PIM1POLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427191-A1 | PESTICIDAL COMPOSITIONS | Dow AgroSciences LLC (US) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010129497-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2010-11-11 | — | — | WO | disclosed |