Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.35 |
| ▸ | ABL1 | P00519 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | POLQ | O75417 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13047770 | 0.91 | PAX8 (0.40) | PAX8DYRK1AABL1ADORA2AADORA2B | |
| SCHEMBL31734141 | 0.91 | PAX8 (0.40) | PAX8DYRK1AABL1ADORA2AADORA2B | |
| SCHEMBL298497 | 0.91 | DYRK1A (0.35) | PAX8DYRK1AABL1ADORA2AADORA2B | |
| SCHEMBL13048770 | 0.90 | PAX8 (0.40) | PAX8DYRK1AABL1ADORA2AADORA2B | |
| SCHEMBL290811 | 0.90 | PAX8 (0.40) | PAX8DYRK1AABL1ADORA2AADORA2B | |
| SCHEMBL3752096 | 0.90 | PAX8 (0.40) | PAX8DYRK1AABL1ADORA2AADORA2B | |
| SCHEMBL19450112 | 0.89 | PAX8 (0.39) | PAX8DYRK1AABL1ADORA2AADORA2B | |
| SCHEMBL17641117 | 0.88 | PIK3CG (0.32) | PAX8DYRK1AABL1PIK3CGTRPM8 | |
| SCHEMBL17589714 | 0.88 | PIK3CG (0.35) | PAX8DYRK1AADORA2AADORA2BPIK3CG | |
| SCHEMBL290441 | 0.87 | PAX8 (0.38) | PAX8DYRK1AABL1ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197276-B1 | HERBICIDAL PYRIDINO-/PYRIMIDINO-THIAZOLES | SYNGENTA PARTICIPATIONS AG (CH) | 2023-06-07 | — | — | EP | disclosed |
| US-20200253208-A1 | HERBICIDAL PYRIDINO-/PYRIMIDINO-THIAZOLES | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-13 | — | — | US | disclosed |
| US-20170290337-A1 | Herbicidal Pyridino-/Pyrimidino-Thiazoles | SYNGENTA PARTICIPATIONS AG (CH) | 2017-10-12 | — | — | US | disclosed |
| US-20170290337-A1 | Herbicidal Pyridino-/Pyrimidino-Thiazoles | SYNGENTA PARTICIPATIONS AG (CH) | 2017-10-12 | — | — | US | disclosed |
| EP-2427191-B1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2016-03-16 | — | — | EP | disclosed |
| US-9006446-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2015-04-14 | — | — | US | disclosed |
| US-9006446-B2 | Pesticidal compositions | DOW AGROSCIENCES LLC (US) | 2015-04-14 | — | — | US | disclosed |
| US-20150045218-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2015-02-12 | — | — | US | disclosed |
| US-20150045218-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2015-02-12 | — | — | US | disclosed |
| US-8853246-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2014-10-07 | — | — | US | disclosed |
| EP-2614825-A1 | Process for the preparation of thiazole derivatives | Dow AgroSciences LLC (US) | 2013-07-17 | — | — | EP | disclosed |
| US-20130089622-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2013-04-11 | — | — | US | disclosed |
| US-20130089622-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2013-04-11 | — | — | US | disclosed |
| US-20130072382-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2013-03-21 | — | — | US | disclosed |
| US-20130072382-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2013-03-21 | — | — | US | disclosed |
| US-8350044-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2013-01-08 | — | — | US | disclosed |
| US-8350044-B2 | Pesticidal compositions | DOW AGROSCIENCES, LLC. (US) | 2013-01-08 | — | — | US | disclosed |
| US-20100292253-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2010-11-18 | — | — | US | disclosed |
| US-20100292253-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2010-11-18 | — | — | US | disclosed |
| WO-2010129497-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2010-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170290337-A1 | Herbicidal Pyridino-/Pyrimidino-Thiazoles | PDXK, PLPBP, DDT | PAX8 1424/4885DYRK1A 681/4885ABL1 641/4885 |
| US-20100292253-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PRDX6 | PAX8 3416/4885DYRK1A 3841/4885ABL1 2834/4885 |
| US-20130089622-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PRDX6 | PAX8 3416/4885DYRK1A 3841/4885ABL1 2834/4885 |
| US-20200253208-A1 | HERBICIDAL PYRIDINO-/PYRIMIDINO-THIAZOLES | PDXK, PLPBP, DDT | PAX8 1424/4885DYRK1A 681/4885ABL1 641/4885 |
| US-20150045218-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PRDX6 | PAX8 3416/4885DYRK1A 3841/4885ABL1 2834/4885 |
| US-20130072382-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, PRDX6 | PAX8 3416/4885DYRK1A 3841/4885ABL1 2834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.