Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.40 |
| ▸ | CTSL | P07711 | 3/20 | 0.39 |
| ▸ | CTSB | P07858 | 3/20 | 0.39 |
| ▸ | CTSS | P25774 | 3/20 | 0.39 |
| ▸ | CTSK | P43235 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2386937 | 0.94 | MEN1 (0.44) | MEN1LMNAKMT2APPARGABCB1 | |
| SCHEMBL2384481 | 0.92 | MEN1 (0.43) | MEN1LMNAKMT2APPARGABCB1 | |
| SCHEMBL5488638 | 0.91 | CTRB1 (0.45) | PPARGABCB1MMEITGB3ITGA2B | |
| SCHEMBL2387351 | 0.85 | ABCB1 (0.47) | PPARGABCB1CTSLCTSBCTSS | |
| SCHEMBL2388325 | 0.85 | ABCB1 (0.41) | MEN1KMT2AABCB1MMEACE | |
| SCHEMBL2388052 | 0.83 | CTSL (0.46) | PPARGABCB1MMEACECTSL | |
| SCHEMBL2385988 | 0.83 | MMP8 (0.44) | LMNAPPARGABCB1CTSLCTSB | |
| SCHEMBL2386438 | 0.83 | TP53 (0.39) | MEN1KMT2AABCB1MMEACE | |
| SCHEMBL2386981 | 0.83 | ABCB1 (0.44) | PPARGABCB1MMEACECPA1 | |
| SCHEMBL2386712 | 0.83 | ATM (0.49) | PPARGABCB1ITGB3ITGA2BCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1980622-B1 | METHOD FOR PRODUCTION OF AN OPTICALLY ACTIVE BIPHENYLALANINE COMPOUND OR SALT OR ESTER THEREOF | SUMITOMO CHEMICAL CO (JP) | 2010-08-18 | — | — | EP | disclosed |
| EP-1980622-A1 | METHOD FOR PRODUCTION OF OPTICALLY ACTIVE BIPHENYLALANINE COMPOUND OR SALT OR ESTER THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-10-15 | — | — | EP | disclosed |