Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 4/20 | 0.33 |
| ▸ | PPARA | Q07869 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29016639 | 0.86 | CSNK1D (0.40) | MRGPRX4KMT2AHDAC6MAPTTP53 | |
| SCHEMBL30370383 | 0.86 | CSNK1D (0.40) | MRGPRX4KMT2AHDAC6MAPTTP53 | |
| SCHEMBL29016646 | 0.81 | PSEN1 (0.39) | KMT2AMAPTSMN1; SMN2CYP3A4LIPG | |
| SCHEMBL30370198 | 0.81 | PSEN1 (0.39) | KMT2AMAPTSMN1; SMN2CYP3A4LIPG | |
| SCHEMBL29016628 | 0.79 | KDM4E (0.47) | MRGPRX4HTTKMT2AHDAC6PPARA | |
| SCHEMBL30370793 | 0.79 | KDM4E (0.47) | MRGPRX4HTTKMT2AHDAC6PPARA | |
| SCHEMBL29016638 | 0.77 | GPR52 (0.43) | MAPTSMN1; SMN2LIPGAKR1B1 | |
| SCHEMBL29016559 | 0.76 | MAPT (0.43) | KMT2AMAPTTP53SMN1; SMN2CYP3A4 | |
| SCHEMBL29016596 | 0.76 | PPARA (0.40) | HTTPDE10AKMT2AHDAC6PPARA | |
| SCHEMBL30370454 | 0.76 | PPARA (0.40) | HTTPDE10AKMT2AHDAC6PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108689942-B | Nitrogen-containing bicyclic compound, and preparation method and application thereof | 广东东阳光药业有限公司 | 2023-06-09 | — | — | CN | disclosed |