Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29870734 | 1.00 | NOS3 (0.47) | NOS3NOS1NOS2L3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL15545578 | 0.98 | NOS1 (0.45) | NOS3NOS1NOS2L3MBTL1ALDH1A1 | |
| SCHEMBL27753903 | 0.92 | NPC1 (0.46) | NOS3NOS1NOS2L3MBTL1ALDH1A1 | |
| SCHEMBL2088060 | 0.85 | NOS3 (0.54) | NOS3NOS1NOS2ALDH1A1DYRK1A | |
| SCHEMBL3401912 | 0.83 | ALDH1A1 (0.56) | L3MBTL1ALDH1A1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL13068145 | 0.81 | ALDH1A1 (0.41) | NOS3NOS1NOS2L3MBTL1ALDH1A1 | |
| SCHEMBL29452983 | 0.80 | ALDH1A1 (0.53) | NOS3NOS1NOS2L3MBTL1ALDH1A1 | |
| SCHEMBL2088106 | 0.80 | NOS3 (0.45) | NOS3NOS1NOS2L3MBTL1ALDH1A1 | |
| SCHEMBL30254429 | 0.80 | NOS3 (0.45) | NOS3NOS1NOS2L3MBTL1ALDH1A1 | |
| SCHEMBL29214462 | 0.80 | ALDH1A1 (0.39) | NOS3NOS1NOS2L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106966993-B | A kind of crude product aftertreatment technology of 2- amino -4,6- dimethoxypyridin preparation | 湖北汇达科技发展有限公司 | 2019-08-30 | — | — | CN | claimed |
| CN-105669798-B | A kind of macrolides compound | 普莱柯生物工程股份有限公司 | 2019-07-26 | — | — | CN | claimed |
| CN-107629009-A | A kind of synthetic method of the dimethoxypyridin of 2 amino of a system 4,6 | 营口营新化工科技有限公司 | 2018-01-26 | — | — | CN | claimed |
| CN-107619393-A | The synthetic method of the dimethoxypyridin of 2 amino 4,6 | 营口营新化工科技有限公司 | 2018-01-23 | — | — | CN | claimed |
| CN-105130909-B | A kind of preparation method of the dimethoxypyridin of 2 amino 4,6 | 湖北汇达科技发展有限公司 | 2017-11-10 | — | — | CN | claimed |
| CN-106966993-A | Crude product post-treatment new process prepared by a kind of dimethoxypyridin of 2 amino 4,6 | 湖北汇达科技发展有限公司 | 2017-07-21 | — | — | CN | claimed |
| CN-105646372-A | Preparation method of 2-amino-4,6-dichloro-5-formamine pyrimidine | 北京英力精化技术发展有限公司 | 2016-06-08 | — | — | CN | claimed |
| CN-103524493-B | The preparation method of nicosulfuron | JIANGSU AGRICULTURAL HORMONE ENGINEERING TECHNOLOGY RESEARCH CENTRE CO., LTD. (CN) | 2016-05-18 | — | — | CN | claimed |
| CN-103865290-B | Fluorine boron fluorescence dye and its preparation method and application | ANHUI NORMAL UNIVERSITY (CN) | 2016-03-30 | — | — | CN | claimed |
| CN-104910165-A | Preparation method of 2-amino-5,7-dimethoxy-triazolopyrimidine | ANHUI SHINDO CHEMICAL CO LTD | 2015-09-16 | — | — | CN | claimed |
| CN-104610167-A | Mesosul furon-methyl synthesis method | UNIV CHINA PHARMA | 2015-05-13 | — | — | CN | claimed |
| CN-102491948-A | Preparation method of 2-amino-4, 6-dimethoxypyrimidine | HUBEI ZHICHENG CHEMICAL TECHNOLOGY CO LTD | 2012-06-13 | — | — | CN | claimed |
| CN-1284773-C | Ortho-pyridinequinone derivative, composite containing said derivative, its preparation method and application | BAIRUI GLOBAL CO LTD (VG) | 2006-11-15 | — | — | CN | claimed |
| CN-1477099-A | O-pyridinoquinone derivative, composition containing the same, preparation method and use of the same | 百瑞全球有限公司 | 2004-02-25 | — | — | CN | claimed |
| CN-1033452-C | Process for the preparation of 1- { [ o- (cyclopropylcarbonyl) -phenyl ] -sulfamoyl } -3- (4, 6-dimethoxy-2-pyrimidinyl) urea | AMERICAN CYANAMID CO (US) | 1996-12-04 | — | — | CN | claimed |
| CN-1057459-A | 1- { [ O- (cyclopropylcarbonyl) -phenyl ] -sulfamoyl } -3- (4, 6-dimethoxy-2-pyrimidinyl) urea and process for preparation thereof | AMERICAN CYANAMID CO (US) | 1992-01-01 | — | — | CN | claimed |
| EP-0074595-B1 | SUBSTITUTED PHENYLSULFONYL UREA DERIVATIVES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION, AND THEIR USE AS HERBICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-07-23 | — | — | EP | claimed |
| EP-4615839-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE | Bristol-Myers Squibb Company (US) | 2025-09-17 | — | — | EP | disclosed |
| CN-1035504-A | 2-amino-4, the production method of 6-dichloro pyrimidine | ISHIHARA SANGYO KAISHA (JP) | 1989-09-13 | — | — | CN | disclosed |
| CN-87100436-A | Substituted pyridine sulfonamide compounds, herbicides containing the same, and process for preparing the same | — | 1987-08-12 | — | — | CN | disclosed |