Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GCK | P35557 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL701660 | 0.80 | TDP1 (0.45) | TDP1ALDH1A1GAATP53MAPT | |
| SCHEMBL701659 | 0.80 | TDP1 (0.45) | TDP1ALDH1A1GAATP53MAPT | |
| SCHEMBL29016755 | 0.79 | TDP1 (0.43) | TDP1ALDH1A1GAATP53KDM4E | |
| SCHEMBL15240826 | 0.73 | ALDH1A1 (0.52) | TDP1ALDH1A1GAATP53MAPT | |
| SCHEMBL701651 | 0.73 | ALDH1A1 (0.52) | TDP1ALDH1A1GAATP53MAPT | |
| SCHEMBL701650 | 0.73 | ALDH1A1 (0.52) | TDP1ALDH1A1GAATP53MAPT | |
| SCHEMBL19047043 | 0.73 | TDP1 (0.47) | TDP1ALDH1A1GAATP53MAPT | |
| SCHEMBL28079197 | 0.73 | LMNA (0.48) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL22556269 | 0.73 | TP53 (0.40) | TDP1ALDH1A1GAATP53MEN1 | |
| SCHEMBL10722944 | 0.70 | TDP1 (0.47) | TDP1ALDH1A1GAATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111566116-B | Novel metal complex, process for producing the same, and process for producing gamma-lactam compound using the same | 基础科学研究院 | 2023-06-09 | — | — | CN | disclosed |