Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11453215 | 0.76 | LMNA (0.54) | LMNAALDH1A1HTTPOLBKMT2A | |
| SCHEMBL2821892 | 0.75 | LMNA (0.60) | LMNATSHRALDH1A1HTTPOLB | |
| SCHEMBL28536859 | 0.73 | LMNA (0.58) | LMNATSHRALDH1A1HTTPOLB | |
| SCHEMBL22556269 | 0.73 | TP53 (0.40) | LMNATSHRALDH1A1HTTPOLB | |
| SCHEMBL29016758 | 0.73 | TDP1 (0.42) | LMNATSHRALDH1A1KMT2AMAPT | |
| SCHEMBL28016614 | 0.71 | ALDH1A1 (0.67) | LMNATSHRALDH1A1HTTPOLB | |
| SCHEMBL5839153 | 0.71 | LMNA (0.60) | LMNAALDH1A1HTTPOLBKMT2A | |
| SCHEMBL22408859 | 0.71 | LMNA (0.49) | LMNAALDH1A1HTTPOLBKMT2A | |
| SCHEMBL22408858 | 0.71 | LMNA (0.49) | LMNAALDH1A1HTTPOLBKMT2A | |
| SCHEMBL10577708 | 0.70 | LMNA (0.68) | LMNATSHRALDH1A1HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105669525-A | Synthetic method of N-((2-(1,3-dioxo-dihydroisoindol-2-yl)-propionyl)-5-methoxy)formamide | 苏州艾缇克药物化学有限公司 | 2016-06-15 | — | — | CN | disclosed |