Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 3/20 | 0.42 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.38 |
| ▸ | SDCBP | O00560 | 2/20 | 0.36 |
| ▸ | SDC2 | P34741 | 2/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 2/20 | 0.35 |
| ▸ | MC3R | P41968 | 2/20 | 0.35 |
| ▸ | MC1R | Q01726 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 4/20 | 0.34 |
| ▸ | FCER2 | P06734 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2906422 | 0.88 | OPRD1 (0.44) | OPRD1KISS1RSDCBPSDC2PSMB8 | |
| SCHEMBL2901655 | 0.85 | OPRD1 (0.44) | OPRD1KISS1RSDCBPSDC2PSMB8 | |
| SCHEMBL2906563 | 0.84 | OPRD1 (0.41) | OPRD1KISS1RSDCBPSDC2PSMB8 | |
| SCHEMBL2906899 | 0.79 | OPRD1 (0.45) | OPRD1KISS1RMMEACECPA1 | |
| SCHEMBL2906545 | 0.78 | OPRD1 (0.39) | OPRD1KISS1RSDCBPSDC2PSMB8 | |
| SCHEMBL2906420 | 0.77 | OPRD1 (0.48) | OPRD1KISS1RSDCBPSDC2PSMB8 | |
| SCHEMBL2898235 | 0.76 | PSMB1 (0.46) | OPRD1PSMB8MMEACECPA1 | |
| SCHEMBL2905590 | 0.75 | KISS1R (0.40) | OPRD1KISS1RDPP4MMEACE | |
| SCHEMBL2905764 | 0.72 | OPRD1 (0.36) | OPRD1KISS1RPSMB8DPP4MC4R | |
| SCHEMBL5556869 | 0.70 | OPRD1 (0.61) | OPRD1SDCBPSDC2CTSCDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2239270-A2 | Low molecular weight peptide derivatives as inhibitors of the Laminin/Nidogen interaction | Sanofi-Aventis Deutschland GmbH (DE) | 2010-10-13 | — | — | EP | disclosed |
| EP-1845106-B1 | Low molecular weight peptide derivatives as inhibitors of the laminin/nidogen interaction | SANOFI AVENTIS DEUTSCHLAND (DE) | 2010-08-11 | — | — | EP | disclosed |
| EP-1845106-A1 | Low molecular weight peptide derivatives as inhibitors of the laminin/nidogen interaction | Sanofi-Aventis Deutschland GmbH (DE) | 2007-10-17 | — | — | EP | disclosed |
| EP-1157040-B1 | LOW MOLECULAR WEIGHT PEPTIDE DERIVATIVES AS INHIBITORS OF THE LAMININ/NIDOGEN INTERACTION | SANOFI AVENTIS DEUTSCHLAND (DE) | 2007-08-22 | — | — | EP | disclosed |
| US-6365572-B1 | FOR THERAPY OF DISEASES RELATED TO INCREASED OR UNWANTED SYNTHESIS OF BASEMENT MEMBRANES SUCH AS DIABETES MELLITUS; ATHEROSCLEROSIS; CANCER; DIABETIC RETINOPATHIA; FIBROPLASIA RETROLENTALIS; OR PSORIASIS, RHEUMATOIC ARTHRITIS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-04-02 | — | — | US | disclosed |