Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1025317 | 1.00 | TSHR (0.34) | TSHRGPR174SLC7A5TP53TGFBR1 | |
| SCHEMBL29016924 | 1.00 | TSHR (0.34) | TSHRGPR174SLC7A5TP53TGFBR1 | |
| Itaconate SCHEMBL10708109 | 0.86 | ALOX15 (0.43) | GPR174 | |
| SCHEMBL7159806 | 0.81 | TDP1 (0.36) | SLC7A5TP53 | |
| SCHEMBL29016903 | 0.81 | TDP1 (0.36) | SLC7A5TP53 | |
| SCHEMBL29016960 | 0.81 | TDP1 (0.36) | SLC7A5TP53 | |
| Acetic Acid SCHEMBL585968 | 0.79 | TSHR (0.35) | TSHRTP53 | |
| SCHEMBL2466487 | 0.78 | TSHR (0.36) | TSHR | |
| SCHEMBL2600786 | 0.78 | TSHR (0.38) | TSHRTP53 | |
| SCHEMBL25086852 | 0.77 | ALDH1A1 (0.39) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116261561-A | Certain chemical compositions and methods of use thereof | 奧基生物技术有限公司 | 2023-06-13 | — | — | CN | disclosed |