⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2895183 | 0.66 | RAB9A (0.38) | — | |
| SCHEMBL7905040 | 0.60 | CYP2A6 (0.44) | — | |
| SCHEMBL2752486 | 0.60 | ALOX5AP (0.39) | — | |
| SCHEMBL1485376 | 0.59 | NISCH (0.42) | — | |
| SCHEMBL2895375 | 0.59 | CYP19A1 (0.34) | — | |
| SCHEMBL21223551 | 0.59 | ADORA2B (0.47) | — | |
| SCHEMBL14796915 | 0.59 | MAPT (0.44) | — | |
| SCHEMBL6375443 | 0.59 | EPHB4 (0.40) | — | |
| SCHEMBL2091591 | 0.58 | METAP2 (0.38) | — | |
| SCHEMBL5539715 | 0.58 | KDM4E (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | BAYER CROPSCIENCE AG (DE) | 2010-12-02 | — | — | US | disclosed |
| EP-2236505-A1 | Acylated aminopyridines and pyridazines as insecticides | Bayer CropScience AG (DE) | 2010-10-06 | — | — | EP | disclosed |