SCHEMBL2901701

SCHEMBL2901701

Cc1ccc2ccc(N)nc2n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 3/20 0.50
NOS3 P29474 2/20 0.50
NOS1 P29475 1/20 0.44
CCR1 P32246 1/20 0.44
RAB9A P51151 1/20 0.44
CCR5 P51681 1/20 0.44
GAA P10253 1/20 0.44
KMT2A Q03164 1/20 0.44
BACE1 P56817 2/20 0.42
NCK1 P16333 1/20 0.42
KDM4E B2RXH2 1/20 0.42
LMNA P02545 1/20 0.42
POLB P06746 1/20 0.42
CASP6 P55212 1/20 0.42
CYP1A2 P05177 2/20 0.38
NCF1 P14598 1/20 0.38
ADORA2A P29274 1/20 0.37
ADORA1 P30542 1/20 0.37
GABRP O00591 1/20 0.36
GABRD O14764 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29414112 1.00 NOS2 (0.50) NOS2NOS3NOS1CCR1RAB9A
SCHEMBL7509409 0.84 CCR1 (0.58) CCR1RAB9ACCR5GAAKMT2A
SCHEMBL1765925 0.84 BACE1 (0.48) NOS2NOS3NOS1KMT2ABACE1
SCHEMBL9849288 0.76 CCR1 (0.44) CCR1RAB9ACCR5GAAKMT2A
SCHEMBL22375095 0.76 RAB9A (0.71) NOS2NOS3NOS1CCR1RAB9A
SCHEMBL10474332 0.76 IDO1 (0.41) NOS2NOS3NOS1BACE1NCK1
SCHEMBL6412343 0.73 PIK3CD (0.40) NOS2NOS3NOS1RAB9AKMT2A
SCHEMBL25748417 0.73 BACE1 (0.54) NOS2NOS3NOS1CCR1RAB9A
SCHEMBL11464475 0.73 NOS2 (0.41) NOS2NOS3NOS1BACE1NCK1
SCHEMBL10758069 0.71 BACE1 (0.43) NOS2NOS3NOS1KMT2ABACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106243105-A Methylene-bridged 1,8 naphthyridines part and copper (I) coordination compound, preparation method and application 红河学院 2016-12-21 CN claimed
US-4169092-A Transition metal-naphthyridine chemical complexes BAYER JOHN W 1979-09-25 US claimed
WO-2025043616-A1 USE OF ACRIDINE DERIVATIVE IN CANCER TREATMENT 侯明宏 2025-03-06 WO disclosed
CN-118562128-A Modified polyimide binder, preparation method thereof, electrode plate and lithium ion battery 东莞东阳光科研发有限公司 2024-08-30 CN disclosed
EP-3286338-B1 AMPLIFICATION WITH PRIMERS OF LIMITED NUCLEOTIDE COMPOSITION Atila Biosystems Incorporated (US) 2023-11-01 EP disclosed
WO-2023176466-A1 VIRUS DETECTION METHOD 国立大学法人九州工業大学 2023-09-21 WO disclosed
CN-114250274-A Amplification of primers with limited nucleotide composition 阿提拉生物系统公司 2022-03-29 CN disclosed
US-20220033891-A1 AMPLIFICATION WITH PRIMERS OF LIMITED NUCLEOTIDE COMPOSITION Atila Biosystems Incorporated (US) 2022-02-03 US disclosed
CN-107849603-B Amplification of primers with limited nucleotide composition 阿提拉生物系统公司 2022-01-28 CN disclosed
EP-3094325-B1 HETEROARYLS AND USES THEREOF TAKEDA PHARMACEUTICALS CO (JP) 2021-10-13 EP disclosed
US-11091799-B2 Amplification with primers of limited nucleotide composition Atila Biosystems Incorporated (US) 2021-08-17 US disclosed
US-4642308-A ANTICONVULSANTS, ANXIOLYTIC AGENTS, ANTIEPILEPTIC AGENTS, HYPNOTICS, MUSCLE RELAXANTS RHONE-POULENC SANTE (FR) 1987-02-10 US disclosed
US-4327095-A TRANQUICIZERS, ANTICONVULSANTS DECONTRACTURANTS AND HYPNOGENIC AGENTS RHONE-POULENC INDUSTRIES (FR) 1982-04-27 US disclosed
US-4169092-A Transition metal-naphthyridine chemical complexes BAYER JOHN W 1979-09-25 US disclosed
US-4124711-A TRANQUILIZERS, ANTICONVULSANTS, DECONTRACTURANTS, HYPNOTIC AGENTS RHONE-POULENC INDUSTRIES (FR) 1978-11-07 US disclosed
US-4038391-A TRANQUILIZERS, ANTICONVULSANTS RHONE-POULENC S.A. (FR) 1977-07-26 US disclosed
US-4021554-A 1,4-Oxathiino[2,3-c]pyrrole derivatives RHONE-POULENC INDUSTRIES (FR) 1977-05-03 US disclosed
US-4016274-A TRANQUILIZERS AND ANTICONVULSANT AGENTS RHONE-POULENC S.A. (FR) 1977-04-05 US disclosed
US-3966931-A TRANQUILIZERS, ANTICONVULSANTS, HYPNOSIS RHONE-POULENC S.A. (FR) 1976-06-29 US disclosed
US-3948917-A TRANQUILIZERS, ANTICONVULSANTS, DECONTRACTURANTS, HYPNOSIS RHONE-POULENC S.A. (FR) 1976-04-06 US disclosed