Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30372833 | 1.00 | POLB (0.48) | POLBNPSR1MAPTLMNAGAA | |
| SCHEMBL29017395 | 0.90 | ALDH1A1 (0.48) | POLBNPSR1MAPTLMNAGAA | |
| SCHEMBL29017334 | 0.88 | POLB (0.51) | POLBLMNAGAAALDH1A1CYP2D6 | |
| SCHEMBL29017340 | 0.87 | CYP2D6 (0.52) | POLBLMNAALDH1A1CYP2D6KMT2A | |
| SCHEMBL29017463 | 0.87 | CYP2D6 (0.52) | POLBLMNAALDH1A1CYP2D6KMT2A | |
| Hydrochloric Acid SCHEMBL9312210 | 0.82 | KDM4E (0.58) | POLBNPSR1MAPTLMNAGAA | |
| SCHEMBL29017377 | 0.81 | CCR3 (0.57) | POLBMAPTLMNAALDH1A1CYP2D6 | |
| SCHEMBL29017359 | 0.80 | CACNA1G (0.56) | POLBALDH1A1CYP2D6MEN1KMT2A | |
| SCHEMBL29017434 | 0.80 | CYP2D6 (0.57) | POLBALDH1A1CYP2D6TSHRSIGMAR1 | |
| Hydrochloric Acid SCHEMBL9312197 | 0.77 | KDM4E (0.67) | POLBALDH1A1KMT2ASIGMAR1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116240194-A | Limonene epoxy hydrolase mutant and catalytic synthesis of chiral oxygen/nitrogen-heterocyclic compound thereof | 中国科学院天津工业生物技术研究所 | 2023-06-09 | — | — | CN | claimed |
| CN-116240194-A | Limonene epoxy hydrolase mutant and catalytic synthesis of chiral oxygen/nitrogen-heterocyclic compound thereof | 中国科学院天津工业生物技术研究所 | 2023-06-09 | — | — | CN | disclosed |