SCHEMBL29017463

SCHEMBL29017463

OC[C@]1(c2ccccc2)CCCN(Cc2ccccc2)C1

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 7/20 0.52
OPRL1 P41146 1/20 0.51
ALDH1A1 P00352 4/20 0.51
POLB P06746 2/20 0.51
TSHR P16473 4/20 0.48
KDM4E B2RXH2 2/20 0.47
KMT2A Q03164 1/20 0.47
CCR3 P51677 1/20 0.47
TACR1 P25103 2/20 0.46
SLC6A4 P31645 2/20 0.46
CYP3A4 P08684 3/20 0.46
LMNA P02545 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29017340 1.00 CYP2D6 (0.52) CYP2D6OPRL1ALDH1A1POLBTSHR
SCHEMBL29017377 0.93 CCR3 (0.57) CYP2D6OPRL1ALDH1A1POLBTSHR
SCHEMBL29017359 0.92 CACNA1G (0.56) CYP2D6ALDH1A1POLBKMT2A
SCHEMBL29017334 0.92 POLB (0.51) CYP2D6OPRL1ALDH1A1POLBTSHR
SCHEMBL29017434 0.88 CYP2D6 (0.57) CYP2D6ALDH1A1POLBTSHRCYP3A4
SCHEMBL30372833 0.87 POLB (0.48) CYP2D6OPRL1ALDH1A1POLBTSHR
SCHEMBL29017446 0.87 POLB (0.48) CYP2D6OPRL1ALDH1A1POLBTSHR
SCHEMBL29017395 0.87 ALDH1A1 (0.48) CYP2D6ALDH1A1POLBTSHRKDM4E
SCHEMBL2511840 0.83 KMT2A (0.55) OPRL1POLBKDM4EKMT2ACCR3
SCHEMBL2789160 0.81 OPRL1 (0.66) CYP2D6OPRL1ALDH1A1POLBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116240194-B Limonene epoxy hydrolase mutant and catalytic synthesis of chiral oxygen/nitrogen-heterocyclic compound thereof 中国科学院天津工业生物技术研究所 2024-11-12 CN claimed
CN-116240194-B Limonene epoxy hydrolase mutant and catalytic synthesis of chiral oxygen/nitrogen-heterocyclic compound thereof 中国科学院天津工业生物技术研究所 2024-11-12 CN disclosed
CN-116240194-A Limonene epoxy hydrolase mutant and catalytic synthesis of chiral oxygen/nitrogen-heterocyclic compound thereof 中国科学院天津工业生物技术研究所 2023-06-09 CN disclosed