Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6429575 | 0.89 | ALDH1A1 (0.53) | ALDH1A1CHRM2CHRM1KCNH2SLC6A3 | |
| SCHEMBL3913293 | 0.88 | ALDH1A1 (0.70) | ALDH1A1CHRM2CHRM1KCNH2SLC6A3 | |
| SCHEMBL5667254 | 0.88 | ALDH1A1 (0.70) | ALDH1A1CHRM2CHRM1KCNH2SLC6A3 | |
| SCHEMBL13574070 | 0.87 | CHRM2 (0.70) | ALDH1A1CHRM2CHRM1KCNH2SLC6A3 | |
| SCHEMBL290176 | 0.87 | CHRM2 (0.70) | ALDH1A1CHRM2CHRM1KCNH2SLC6A3 | |
| SCHEMBL13574067 | 0.87 | CHRM2 (0.70) | ALDH1A1CHRM2CHRM1KCNH2SLC6A3 | |
| SCHEMBL4632283 | 0.80 | KEAP1 (0.72) | ALDH1A1CHRM2CHRM1KCNH2SLC6A3 | |
| SCHEMBL5746892 | 0.78 | KEAP1 (0.51) | ALDH1A1CHRM2CHRM1KCNH2SLC6A3 | |
| SCHEMBL2763519 | 0.78 | KEAP1 (0.70) | ALDH1A1CHRM2CHRM1KCNH2SLC6A3 | |
| SCHEMBL31078935 | 0.78 | ALDH1A1 (0.49) | ALDH1A1CHRM2CHRM1KCNH2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105221-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105221-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | CHRM3, CHRM5, CHRM2 | ALDH1A1 1361/4885CHRM2 3/4885CHRM1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.