Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HSD17B3 | P37058 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CETP | P11597 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DGKA | P23743 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL29018005 | 1.00 | L3MBTL1 (0.49) | L3MBTL1HSD17B3NPC1RAB9AALDH1A1 | |
| Phosphoric Acid SCHEMBL29018004 | 0.94 | LMNA (0.45) | L3MBTL1HSD17B3ALDH1A1MAPTTDP1 | |
| SCHEMBL27818338 | 0.93 | L3MBTL1 (0.47) | L3MBTL1HSD17B3NPC1RAB9AALDH1A1 | |
| SCHEMBL28060939 | 0.91 | L3MBTL1 (0.48) | L3MBTL1HSD17B3NPC1RAB9AALDH1A1 | |
| Phosphoric Acid SCHEMBL29018246 | 0.88 | TDP1 (0.46) | L3MBTL1NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL9016067 | 0.88 | HSD17B3 (0.51) | HSD17B3NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL22655275 | 0.88 | HSD17B3 (0.51) | HSD17B3NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL28374530 | 0.82 | HSD17B3 (0.63) | HSD17B3NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL8445562 | 0.82 | TP53 (0.55) | ALDH1A1MAPTKMT2A | |
| SCHEMBL1615178 | 0.82 | HSD17B3 (0.63) | HSD17B3NPC1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113929798-B | Solid catalyst component and catalyst system for olefin polymerization | 中国石油化工股份有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-113929797-B | Solid catalyst component and catalyst system for producing polymers | 中国石油化工股份有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-113929799-B | Catalyst component for olefin polymerization, catalyst system and use | 中国石油化工股份有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-114085301-B | Solid catalyst component for preparing olefin polymer and application thereof | 中国石油化工股份有限公司 | 2023-05-09 | — | — | CN | disclosed |