Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 10/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29019236 | 0.92 | LCK (0.39) | LCKMAPTGSK3BDYRK1A | |
| SCHEMBL29019243 | 0.89 | LCK (0.39) | LCKGSK3BDYRK1A | |
| SCHEMBL30186700 | 0.81 | LCK (0.36) | LCKLMNAGSK3BDYRK1A | |
| SCHEMBL30186689 | 0.79 | LCK (0.34) | LCKMEN1LMNAPOLBKMT2A | |
| SCHEMBL2520077 | 0.78 | TRPM8 (0.53) | MEN1LMNAKMT2AALDH1A1MAPT | |
| SCHEMBL30186682 | 0.77 | TRPM8 (0.35) | LCKMEN1KMT2AADORA2AADORA3 | |
| SCHEMBL18039588 | 0.75 | TRPM8 (0.42) | LCKMEN1LMNAKMT2AALDH1A1 | |
| SCHEMBL15572179 | 0.73 | LCK (0.39) | LCKMEN1LMNAKMT2AALDH1A1 | |
| SCHEMBL2826113 | 0.72 | TSHR (0.41) | LCKLMNAALDH1A1MAPTPKM | |
| SCHEMBL12080070 | 0.71 | TSHR (0.40) | LCKMEN1LMNAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096725-A | Compounds and methods for modulating splicing | 雷密克斯医疗公司 | 2023-05-09 | — | — | CN | disclosed |
| EP-4132935-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | Remix Therapeutics Inc. (US) | 2023-02-15 | — | — | EP | disclosed |