Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 14/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29019233 | 0.92 | LCK (0.37) | LCKGSK3BDYRK1AMAPT | |
| SCHEMBL29019243 | 0.91 | LCK (0.39) | LCKGSK3BDYRK1AIRAK4 | |
| SCHEMBL30186700 | 0.83 | LCK (0.36) | LCKGSK3BDYRK1AIRAK4 | |
| SCHEMBL30186689 | 0.81 | LCK (0.34) | LCKGSK3BDYRK1AMAPTHTT | |
| SCHEMBL19899530 | 0.72 | L3MBTL1 (0.41) | LCKRAF1SMN1; SMN2 | |
| SCHEMBL19899715 | 0.71 | L3MBTL1 (0.41) | LCKRAF1SMN1; SMN2 | |
| SCHEMBL29450135 | 0.71 | L3MBTL1 (0.41) | LCKRAF1SMN1; SMN2 | |
| SCHEMBL28048974 | 0.71 | LCK (0.43) | LCKRAF1CYP2C9CYP2C19NPSR1 | |
| SCHEMBL21781666 | 0.71 | RAF1 (0.44) | LCKRAF1NPSR1 | |
| SCHEMBL19912152 | 0.71 | L3MBTL1 (0.40) | LCKRAF1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096725-A | Compounds and methods for modulating splicing | 雷密克斯医疗公司 | 2023-05-09 | — | — | CN | disclosed |