Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 14/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29019236 | 0.91 | LCK (0.39) | LCKGSK3BDYRK1AIRAK4 | |
| SCHEMBL29019233 | 0.89 | LCK (0.37) | LCKGSK3BDYRK1A | |
| SCHEMBL30186700 | 0.84 | LCK (0.36) | LCKGSK3BDYRK1AIRAK4 | |
| SCHEMBL30186689 | 0.82 | LCK (0.34) | LCKGSK3BDYRK1A | |
| SCHEMBL28048974 | 0.80 | LCK (0.43) | LCKBRD9 | |
| SCHEMBL2521682 | 0.76 | KDM4E (0.48) | LCKBRD9 | |
| SCHEMBL2524367 | 0.73 | KDM4E (0.48) | LCK | |
| SCHEMBL6523055 | 0.73 | LCK (0.47) | LCK | |
| SCHEMBL2519144 | 0.72 | LCK (0.44) | LCK | |
| SCHEMBL2520688 | 0.72 | USP30 (0.40) | LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096725-A | Compounds and methods for modulating splicing | 雷密克斯医疗公司 | 2023-05-09 | — | — | CN | disclosed |
| EP-4132935-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | Remix Therapeutics Inc. (US) | 2023-02-15 | — | — | EP | disclosed |