SCHEMBL29019889

SCHEMBL29019889

Nc1ccc(-c2cccc(O)c2S(=O)(=O)O)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.42
TSHR P16473 4/20 0.42
NT5E P21589 3/20 0.42
DAPK1 P53355 1/20 0.41
CA12 O43570 4/20 0.40
CA1 P00915 4/20 0.40
CA2 P00918 4/20 0.40
CA9 Q16790 4/20 0.40
CA14 Q9ULX7 3/20 0.40
AURKA O14965 1/20 0.38
AURKB Q96GD4 1/20 0.38
HSD17B10 Q99714 4/20 0.38
TDP1 Q9NUW8 4/20 0.38
AR P10275 1/20 0.38
MAOA P21397 2/20 0.37
HPGD P15428 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
TP53 P04637 1/20 0.37
GLA P06280 1/20 0.37
CYP3A4 P08684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29700247 0.84 ALDH1A1 (0.54) ALDH1A1TSHRDAPK1HSD17B10TDP1
SCHEMBL3042569 0.84 ALDH1A1 (0.54) ALDH1A1TSHRDAPK1HSD17B10TDP1
SCHEMBL5167481 0.83 MEN1 (0.42) ALDH1A1TSHRCA12CA1CA2
Formaldehyde SCHEMBL5123936 0.81 ALDH1A1 (0.50) ALDH1A1TSHRDAPK1HSD17B10TDP1
SCHEMBL23433029 0.76 LMNA (0.46) ALDH1A1DAPK1HSD17B10HPGDSMN1; SMN2
SCHEMBL4163078 0.76 MAOA (0.43) ALDH1A1TSHRDAPK1CA12CA2
SCHEMBL1270822 0.75 ALDH1A1 (0.45) ALDH1A1TSHRNT5EDAPK1CA12
SCHEMBL29566314 0.75 ALDH1A1 (0.45) ALDH1A1TSHRNT5EDAPK1CA12
SCHEMBL582872 0.74 ALDH1A1 (0.43) ALDH1A1TSHRDAPK1CA12CA1
SCHEMBL1755214 0.74 AURKA (0.49) ALDH1A1TSHRNT5EDAPK1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114478609-B Method for using thiophenol photocatalyst in defluorination alkylation or defluorination protonation reaction 中国科学技术大学 2023-06-16 CN disclosed