Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2952830 | 0.70 | CA1 (0.52) | CA1CA9MAPTSMN1; SMN2KDM4E | |
| SCHEMBL5409295 | 0.69 | SHMT2 (0.35) | MAPTSMN1; SMN2HTTGAAHSD17B10 | |
| SCHEMBL22149740 | 0.67 | CA1 (0.44) | CA1CA9MAPTSMN1; SMN2KDM4E | |
| SCHEMBL22149504 | 0.67 | CA1 (0.44) | CA1CA9MAPTSMN1; SMN2KDM4E | |
| SCHEMBL627794 | 0.67 | IDH1 (0.39) | SMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL6121460 | 0.66 | CA1 (0.52) | CA1CA9MAPTSMN1; SMN2KDM4E | |
| SCHEMBL29016899 | 0.62 | MAPT (0.30) | MAPT | |
| SCHEMBL9431126 | 0.62 | CA1 (0.39) | CA1CA9MAPTSMN1; SMN2KDM4E | |
| SCHEMBL8368041 | 0.62 | CA1 (0.56) | CA1CA9MAPTSMN1; SMN2KDM4E | |
| SCHEMBL29229615 | 0.61 | KDM4E (0.32) | KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110963964-B | Continuous synthesis method of piroctone | 湖南华腾医药有限公司 | 2023-08-15 | — | — | CN | claimed |
| CN-117088811-B | Preparation method of anti-dandruff agent intermediate piroctone | 安庆科思化学有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-117088811-A | Preparation method of anti-dandruff agent intermediate piroctone | 安庆科思化学有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-110963964-B | Continuous synthesis method of piroctone | 湖南华腾医药有限公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-110372654-B | Method for synthesizing 4-methyl-6- (2, 4-trimethyl amyl) -2H-pyran-2-ketone by two-step method | 成武县晨晖环保科技有限公司 | 2023-05-23 | — | — | CN | disclosed |